PA007393.m1: In vivo Grade Recombinant Anti-human CD64 Monoclonal Antibody, Mouse IgG1 Kappa (Clone: M22)

Recombinant mouse IgG1 Monoclonal Antibody. 
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: M22) specifically binds to human CD64.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human CD64 protein. Human Fc receptor blocking solution, human Fc receptor blocking reagent, and human Fc receptor blocking antibody.

PA007393.h1Fs: In vivo Grade Recombinant Anti-human CD64 Monoclonal Antibody, Human IgG1 Fc Silent Kappa (Clone: H22)

Recombinant human IgG1 monoclonal antibody with Fc silent mutation. 
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: H22) specifically binds to human CD64.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human CD64 protein. Human Fc receptor blocking solution, human Fc receptor blocking reagent, and human Fc receptor blocking antibody.

BP003305: Human IL-23 P19/IL-23A Protein with the C-hFc Tag

Source: The recombinant Human IL-23 P19/IL-23A Protein, (amino acids Arg20-Pro189) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003924: Mouse IL-23R Protein with the C-His Tag

Source: The recombinant Mouse IL-23R Protein, (amino acids Gly24-Gly374) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: The affinity constant of 6.31 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005180: Mouse IL-23 alpha&IL-12 beta Protein with the N-His Tag

Source: The recombinant Mouse IL-23 alpha&IL-12 beta Protein, (amino acids Val22-Ala196(IL-23 alpha) & Met23-Ser335(IL-12 beta)) fused with a His tag at the N-terminus, was produced in HEK 293 cells.
Activity: The affinity constant of 6.31 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003947: Human IL-23R Protein with the C-His Tag

Source: The recombinant Human IL-23R Protein, (amino acids Gly24-Gly355) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human IL-23R protein with the C-His tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human IL-23 alpha&IL-12 beta protein with the C-His tag with the EC50 of 2.75 ug/ml determined by ELISA (QC Test). The affinity constant of 5.72 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003311: Human IL-23R Protein with the C-hFc Tag

Source: The recombinant Human IL-23R Protein, (amino acids Gly24-Gly355) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Biotinylated Human IL-23 alpha&IL-12 beta protein with the C-hFc tag at 2 ug/ml (100 ul/well) on the streptavidin precoated plate (5 ug/ml). Dose response curve for the recombinant Human IL-23R protein with the C- hFc tag with the EC50 of 21.0 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005408: Human IL-23R Protein with the C-mFc Tag

Source: The recombinant Human IL-23R Protein, (amino acids Gly24-Gly355) fused with a mFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Biotinylated Human IL-23 alpha&IL-12 beta protein with the C-mFc tag at 2 ug/ml (100 ul/well) on the streptavidin precoated plate (5 ug/ml). Dose response curve for the recombinant Human IL-23R protein with the C-mFc tag with the EC50 of 11.1 ng/ml determined by ELISA (QC Test). The affinity constant of 11.09 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005285: Human IL-23 alpha&Mouse IL-12 beta Protein with the C-His-Avi Tag

Source: The recombinant Human IL-23 alpha&Mouse IL-12 beta Protein, (amino acids Arg20-Pro189(Human IL-23 alpha) & Met23-Ser335(Mouse IL-12 beta)) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human IL-23 alpha&Mouse IL-12 beta protein with the C-His-Avi tag at 5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Human IL-23R protein with the C-mFc tag with the EC50 of 0.15 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003255: Human IL-23 alpha&IL-12 beta Protein with the C-His Tag

Source: The recombinant Human IL-23 alpha&IL-12 beta Protein, (amino acids Arg20-Pro189(IL-23 alpha) & Ile23-Ser328(IL-12 beta)) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human IL-23 alpha&IL-12 beta protein with the C-His tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-IL-23 Antibody protein with the C-hFc tag with the EC50 of 3.3 ng/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003938: Cynomolgus IL-23R Protein with the C-His Tag

Source: The recombinant Cynomolgus IL-23R Protein, (amino acids Gly24-Asp353) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus IL-23R protein with the C-His tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human IL-23 alpha&IL-12 beta protein with the C-His tag with the EC50 of 0.39 ug/ml determined by ELISA (QC Test). The affinity constant of 3.90 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005089: Cynomolgus IL-23 alpha&Mouse IL-12 beta Protein with the N-His Tag

Source: The recombinant Cynomolgus IL-23 alpha&Mouse IL-12 beta Protein, (amino acids Val22-Pro189(Cynomolgus IL-23 alpha) & Met23-Ser335(Mouse IL-12 beta)) fused with a His tag at the N-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus IL-23 alpha&Mouse IL-12 beta protein with the N-His tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human IL-23R protein with the N-hFc tag with the EC50 of 57.5 ng/ml determined by ELISA (QC Test). The affinity constant of 3.90 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003865: Canine IL-23R Protein with the C-His Tag

Source: The recombinant Canine IL-23R Protein, (amino acids Gly24-Asp354) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Canine IL-23R protein with the C-His tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human IL-23 alpha&IL-12 beta protein with the C-His tag with the EC50 of 2.7 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.