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Human IL-23R Protein

IBD17; IL-23 R; IL-23 receptor

Catalog No. Product Name Size List Price (US$) Quantity
BP003947 Human IL-23R Protein with the C-His Tag 100UG 315.00
BP003947 Human IL-23R Protein with the C-His Tag 500UG 1050.00
BP003311 Human IL-23R Protein with the C-hFc Tag 100UG 315.00
BP003311 Human IL-23R Protein with the C-hFc Tag 500UG 1050.00
BP005408 Human IL-23R Protein with the C-mFc Tag 100UG 315.00
BP005408 Human IL-23R Protein with the C-mFc Tag 500UG 1050.00
Description

BP003947: Human IL-23R Protein with the C-His Tag

Source: The recombinant Human IL-23R Protein, (amino acids Gly24-Gly355) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Molecular Weight: The recombinant Human IL-23R protein with the His tag at the C-terminus has a predicted MW of 39.15 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Tris-Bis PAGE result.
Activity: Immobilized recombinant Human IL-23R protein with the C-His tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human IL-23 alpha&IL-12 beta protein with the C-His tag with the EC50 of 2.75 ug/ml determined by ELISA (QC Test). The affinity constant of 5.72 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.
Formulation: Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution: It is recommended to reconstitute the lyophilized recombinant Human IL-23R Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.

BP003311: Human IL-23R Protein with the C-hFc Tag

Source: The recombinant Human IL-23R Protein, (amino acids Gly24-Gly355) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Molecular Weight: The recombinant Human IL-23R protein with the hFc tag at the C-terminus has a predicted MW of 64.81 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
Activity: Immobilized recombinant Biotinylated Human IL-23 alpha&IL-12 beta protein with the C-hFc tag at 2 ug/ml (100 ul/well) on the streptavidin precoated plate (5 ug/ml). Dose response curve for the recombinant Human IL-23R protein with the C- hFc tag with the EC50 of 21.0 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.
Formulation: Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution: It is recommended to reconstitute the lyophilized recombinant Human IL-23R Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.

BP005408: Human IL-23R Protein with the C-mFc Tag

Source: The recombinant Human IL-23R Protein, (amino acids Gly24-Gly355) fused with a mFc tag at the C-terminus, was produced in HEK 293 cells.
Molecular Weight: The recombinant Human IL-23R protein with the mFc tag at the C-terminus has a predicted MW of 63.7 kDa. Due to glycosylation, the protein migrates to 80-115 kDa based on Tris-Bis PAGE result.
Activity: Immobilized recombinant Biotinylated Human IL-23 alpha&IL-12 beta protein with the C-mFc tag at 2 ug/ml (100 ul/well) on the streptavidin precoated plate (5 ug/ml). Dose response curve for the recombinant Human IL-23R protein with the C-mFc tag with the EC50 of 11.1 ng/ml determined by ELISA (QC Test). The affinity constant of 11.09 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.
Formulation: Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution: It is recommended to reconstitute the lyophilized recombinant Human IL-23R Protein in sterile H2O to a protein concentration not less than 100 ug/ml. Centrifuge the tube before opening.


Shipping: The recombinant Human IL-23R Protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 week, 2 to 8°C under sterile conditions after reconstitution.
6 months, -20 to -70°C under sterile conditions after reconstitution.

Syd Labs provides the following IL-23 alpha& IL-12 beta Protein :
Biotinylated Human IL-23 alpha&IL-12 beta Protein
Biotinylated Human IL-23 alpha&Mouse IL-12 beta Protein
Cynomolgus IL-23 alpha&Mouse IL-12 beta Protein
Human IL-23 alpha&IL-12 beta Protein
Human IL-23 alpha&Mouse IL-12 beta Protein
Mouse IL-23 alpha&IL-12 beta Protein

Syd Labs provides the following IL-23 Protein :
Biotinylated Mouse IL-23A Protein
Human IL-23 P19 Protein
Canine IL-23R Protein
Cynomolgus IL-23R Protein
Human IL-23R Protein
Mouse IL-23R Protein

Syd Labs provides the following IL-23 Antibody :
Briakinumab Biosimilar, IL-12 / IL-23 Monoclonal Antibody
IL-23 Antibody
Ustekinumab Biosimilar, IL-12 / IL-23 Monoclonal Antibody

Syd Labs provides the following IL-23 ELISA Kit :
Mouse IL-23 ELISA Kit

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