BP004943: Biotinylated Cynomolgus GDF15 Protein with the N-hFc Tag

Source: The recombinant Biotinylated Cynomolgus GDF15 Protein, (amino acids Ala197-Val308) fused with a hFc tag at the N-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus GFRAL protein with the N-hFc tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Biotinylated Cynomolgus GDF15 protein with the N-hFc tag with the EC50 of 4.8 ng/ml determined by ELISA..
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP004144: Biotinylated Human GDF15 Protein with the N-His-Avi Tag

Source: The recombinant Biotinylated Human GDF15 Protein, (amino acids Ala197-Ile308) fused with a His-Avi tag at the N-terminus, was produced in E.coli cells.
Activity: Immobilized recombinant Human GFRAL protein with the N-His-Avi tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Biotinylated Human GDF15 protein with the N-His tag with the EC50 of 24 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005010: Biotinylated Human GDF15 Protein with the N-hFc Tag

Source: The recombinant Biotinylated Human GDF15 Protein, (amino acids Ala197-Ile308) fused with a hFc tag at the N-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human GFRAL protein with the N-hFc tag at 0.5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Biotinylated Human GDF15 protein with the N-hFc tag with the EC50 of 7.0 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP004875: Biotinylated Mouse GDF15 Protein with the N-hFc Tag

Source: The recombinant Biotinylated Mouse GDF15 Protein, (amino acids Ser189-Ala303) fused with a hFc tag at the N-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Mouse GFRAL protein with the N-hFc tag at 2 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Biotinylated Mouse GDF15 protein with the N-hFc tag with the EC50 of 10 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP004043: Cynomolgus GDF15 Protein with the N-His Tag

Source: The recombinant Cynomolgus GDF15 Protein, (amino acids Arg193-Val308) fused with a His tag at the N-terminus, was produced in E.coli cells.
Activity: Immobilized recombinant Cynomolgus GDF15 protein with the N-His tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Cynomolgus GFRAL protein with the N-His tag with the EC50 of 101.8 ng/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005008: Cynomolgus GDF15 Protein with the N-hFc Tag

Source: The recombinant Cynomolgus GDF15 Protein, (amino acids Ala197-Val308) fused with a hFc tag at the N-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus GFRAL protein with the N-hFc tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Cynomolgus GDF15 protein with the N-hFc tag with the EC50 of 3.6 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP000070-CYT-314: Recombinant Human Growth and Differentiation Factor 15 D-Variant

Source: E. coli-derived.
Purity > 95%, by SDS-PAGE and RP-HPLC.

BP000070-CYT-335: Recombinant Human Growth and Differentiation Factor 15

Source: E. coli-derived.
The biological activity was assessed by the inhibition of DU-145 cells and was found to be 1-2 ug/ml.
Purity > 95%, by SDS-PAGE and RP-HPLC.

BP000070-CYT-691: Recombinant Human Growth and Differentiation Factor 15, His Tag

Source: E. coli-derived.
Purity > 95%, by SDS-PAGE.

BP004307: Human GDF15 Protein with the N-His Tag

Source: The recombinant Human GDF15 Protein, (amino acids Ala197-Ile308) fused with a His tag at the N-terminus, was produced in E.coli cells.
Activity: Immobilized recombinant Human GDF15 protein with the N-His tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human GFRAL protein with the N-hFc tag with the EC50 of 11.5 ng/ml determined by ELISA (QC Test). The affinity constant of 0.014 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP004865: Human GDF15 Protein with the N-hFc Tag

Source: The recombinant Human GDF15 Protein, (amino acids Ala197-Ile308) fused with a hFc tag at the N-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human GFRAL protein with the N-hFc tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human GDF15 protein with the N-hFc tag with the EC50 of 2.5 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP000140-CYT-378: Recombinant Mouse Interleukin-17 (IL-17) Protein

Source: E. coli-derived.
The ED50 as determined by the dose-dependant induction of IL-6 production in cultured mouse NIH 3T3 fibroblasts was found to be 0.4 ng/ml, corresponding to a specific activity of 2,500,000 units/mg.
Purity: > 98% by SDS-PAGE and RP-HPLC.

BP000140-CYT-542: Recombinant Rat Interleukin-17 (IL-17) Protein

Source: E. coli-derived.
Rat IL-17A is fully biologically active when compared to standards via dose-dependent induction of IL-6 production in cultured mouse NIH 3T3 fibroblasts. The ED50 for recombinant rat IL-17A in this assay was 30 ng/ml. The Specific Activity is 33333.33 units/mg.
Purity: > 95% by SDS-PAGE and RP-HPLC.