C104P: Dupilumab Biosimilar, IL4R alpha Monoclonal Antibody
Recombinant fully human IgG4 monoclonal antibody.
Specificity/Sensitivity: The monoclonal antibody dupilumab biosimilar specifically binds to the human IL4R alpha.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by dupilumab.BP005209: Human IL-4 Protein with No Tag
Source: The recombinantHuman IL-4 Protein, (amino acids His25-Ser153) fused with No Tag, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human IL-4, No tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human IL-4 R alpha, hFc tag with the EC50 of 9.8 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP005694: Human IL-4 Protein with the C-His-Avi Tag
Source: The recombinant Human IL-4 Protein, (amino acids His25-Ser153) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human IL-4 protein with the C-His-Avi tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human IL-4 R alpha protein with the C-hFc tag with the EC50 of 4.2 ng/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP005343: Biotinylated Human IL-4 Protein with the C-His-Avi Tag
Source: The recombinant Biotinylated Human IL-4 Protein, (amino acids His25-Ser153) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human IL-4 R alpha protein with the C-His-Avi tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Biotinylated Human IL-4 protein with the C-His tag with the EC50 of 11.3 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.PA007534.r1: In Vivo Grade Recombinant Anti-mouse IL-4 Monoclonal Antibody (Clone: 11B11), Rat IgG1 Kappa
Recombinant rat IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: 11B11) specifically binds to mouse IL-4.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse IL-4 protein.PA006340-PA1618: IL4R Polyclonal Antibody
Rabbit Polyclonal Antibody;
Applications: WB, IHC-P;
Reactivity: Human;
Isotype: Rabbit IgG.PA007810.r1: Recombinant Anti-mouse IL-4 Monoclonal Antibody (Clone: 11B11), Rat IgG1 Kappa
Recombinant rat IgG2a Monoclonal Antibody.
Specificity/Sensitivity: The recombinant 11B11 antibody specifically binds to mouse IL-4.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).PA007810.h1Fs: Recombinant Anti-mouse IL-4 Monoclonal Antibody (Clone: 11B11), Human IgG1 Fc Silent Kappa
Recombinant Human IgG1 Monoclonal Antibody with Fc silent mutation.
Specificity/Sensitivity: The recombinant 11B11 antibody specifically binds to mouse IL-4.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).PA007811.h1Fs-b: Biotinylated Recombinant Anti-mouse IL-4 Monoclonal Antibody (Clone: 11B11), Human IgG1 Fc Silent Kappa
Recombinant human IgG1 monoclonal antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
Specificity/Sensitivity: The site-directed biotinylated recombinant 11B11 antibody specifically binds to mouse IL-4.
Applications: Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.BP000158-CYT-212: Recombinant Human IL-5
Source: E. coli-derived.
The ED50 as determined by the dose-dependant stimulation of the proliferation of TF-1 cells was found to be < 0.15 ug/ml, corresponding to a Specific Activity of 6.7 MIU/mg.
Purity > 98%, by SDS-PAGE and RP-HPLC.BP000158-CYT-387: Recombinant Rat IL-5
Source: E. coli-derived.
The ED50 range=0.3-1.0 ug/ml as determined by the dose-dependant stimulation of the proliferation of BCL-1 cells.
Purity > 95%, by SDS-PAGE and RP-HPLC.BP000158-CYT-689: Recombinant Mouse IL-5
Source: E. coli-derived.
The ED50 as determined by the dose-dependant stimulation of the proliferation of TF-1 cells was found to be 1.7 ug/ml, corresponding to a specific activity of 588,235.3 IU/mg.
Purity > 97%, by SDS-PAGE and RP-HPLC.BP000157-CYT-271: Recombinant Human Interleukin-4 (IL-4) Protein, CHO
Source: Chinese Hamster Ovarian Cells-derived.
Measured in a cell proliferation assay using TF-1 cells. The ED50 for this effect is 0.05-0.2 ug/ml corresponding to a Specific Activity of 5-20 MIU/mg.
Purity: > 97% by SDS-PAGE and RP-HPLC.