PA007594.r1:In Vivo Grade Recombinant Anti-human IL-12 Monoclonal Antibody (Clone: 20C2), Rat IgG1 Kappa

Recombinant Rat IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: 20C2) specifically binds to human IL-12.
Applications:ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human IL-12 protein.

PA007574.r2a: In Vivo Grade Recombinant Anti-mouse IL-12 Monoclonal Antibody (Clone: R1-5D9), Rat IgG2a Kappa

Recombinant Rat IgG2a Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: R1-5D9) specifically binds to mouse IL-12.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse IL-12 protein.

PA007866.r2a: Recombinant Anti-mouse IL-12 Monoclonal Antibody (Clone: R1-5D9), Rat IgG2a Kappa

Recombinant Rat IgG2a Kappa Monoclonal Antibody.
Clone: R1-5D9.
Isotype: Rat IgG2a Kappa.
Source: The anti-mouse IL-12 monoclonal antibody (clone: R1-5D9) was produced in mammalian cells.
Conjugation: non-conjugated.
Specificity/Sensitivity: The recombinant R1-5D9 antibody specifically binds to mouse IL-12.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.

PA007866.h1Fs: Recombinant Anti-mouse IL-12 Monoclonal Antibody (Clone: R1-5D9), Human IgG1 Fc Silent Kappa

Recombinant Human IgG1 Monoclonal Antibody with Fc silent mutation.
Clone: R1-5D9.
Isotype: Human IgG1 Fc Silent Kappa.
Source: The anti-mouse IL-12 monoclonal antibody (clone: R1-5D9) was produced in mammalian cells.
Conjugation: non-conjugated.
Specificity/Sensitivity: The recombinant R1-5D9 antibody specifically binds to mouse IL-12.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.

PA007867.h1Fs-b: Biotinylated Recombinant Anti-mouse IL-12 Monoclonal Antibody (Clone: R1-5D9), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 monoclonal antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
Clone: R1-5D9.
Isotype: Human IgG1 Fc Silent Kappa.
Source: The site-directed biotinylated anti-mouse IL-12 monoclonal antibody (clone: R1-5D9) was produced in mammalian cells.
Conjugation:  Biotin-conjugated.
Specificity/Sensitivity: The site-directed biotinylated recombinant R1-5D9 antibody specifically binds to mouse IL-12.
Applications: Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.

Shipping: The recombinant anti-mouse IL-12 monoclonal antibody of clone R1-5D9 is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month from date of receipt, 2 to 8°C as supplied.

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PA007866.r2a: Recombinant Anti-mouse IL-12 Monoclonal Antibody (Clone: R1-5D9), Rat IgG2a Kappa

Recombinant Rat IgG2a Kappa Monoclonal Antibody.
Specificity/Sensitivity: The recombinant R1-5D9 antibody specifically binds to mouse IL-12.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007866.h1Fs: Recombinant Anti-mouse IL-12 Monoclonal Antibody (Clone: R1-5D9), Human IgG1 Fc Silent Kappa

Recombinant Human IgG1 Monoclonal Antibody with Fc silent mutation.
Specificity/Sensitivity: The recombinant R1-5D9 antibody specifically binds to mouse  IL-12.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007867.h1Fs-b: Biotinylated Recombinant Anti-mouse IL-12 Monoclonal Antibody (Clone: R1-5D9), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 monoclonal antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
Specificity/Sensitivity: The site-directed biotinylated recombinant R1-5D9 antibody specifically binds to mouse  IL-12.
Applications: Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.

PA007570.r2b: In Vivo Grade Recombinant Anti-mouse IL-12 p75 Monoclonal Antibody (Clone: R2-9A5), Rat IgG2b Kappa

Recombinant rat IgG2b Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: R2-9A5) specifically binds to mouse IL-12 p75.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse IL-12 p75 protein.

PA007860.r2b: Recombinant Anti-mouse IL-12 p75 Monoclonal Antibody (Clone: R2-9A5), Rat IgG2b Kappa

Recombinant Rat IgG2b Kappa Monoclonal Antibody.
Specificity/Sensitivity: The recombinant R2-9A5 antibody specifically binds to mouse IL-12 p75.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007860.h1Fs: Recombinant Anti-mouse IL-12 p75 Monoclonal Antibody (Clone: R2-9A5), Human IgG1 Fc Silent Kappa

Recombinant Human IgG1 Monoclonal Antibody with Fc silent mutation.
Specificity/Sensitivity: The recombinant R2-9A5 antibody specifically binds to mouse  IL-12 p75.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007861.h1Fs-b: Biotinylated Recombinant Anti-mouse IL-12 p75 Monoclonal Antibody (Clone: R2-9A5), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 monoclonal antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
Specificity/Sensitivity: The site-directed biotinylated recombinant R2-9A5 antibody specifically binds to mouse  IL-12 p75.
Applications: Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.

BP005012: Biotinylated Human IL-12 Protein with the C-His-Avi Tag

Source: The recombinant Biotinylated Human IL-12 Protein, (amino acids Ile23-Ser328(IL-12B) & Arg23-Ser219(IL-12A)) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Anti-IL-12 Antibody protein with the C-His-Avi tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human IL-12 protein with the C-His tag with the EC50 of 10.8 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

C041P: Briakinumab Biosimilar, IL-12 / IL-23 Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade briakinumab biosimilar specifically binds to the human interleukin-12 (IL-12) and interleukin-23 (IL-23).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by briakinumab.

C121P: Guselkumab Biosimilar, Human IL-23 Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody. 
Specificity/Sensitivity: The in vivo grade guselkumab biosimilar specifically binds to the IL-23 protein.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by guselkumab.

BP005622: Human IL-12 Protein with the C-His-Avi Tag

Source: The recombinant Human IL-12 Protein, (amino acids Ile23-Ser328(IL-12B) & Arg23-Ser219(IL-12A)) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human IL-12 protein with the C-His-Avi tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-IL-12 Antibody protein with the C-hFc tag with the EC50 of 2.1 ng/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP002449-CYT-050: Recombinant Human Interleukin-23 (IL 23) Protein

Source: HEK-derived.
The activity, as determined by the dose dependent secretion of h-IFN-g from human PBMC was found to be 2 to 20 ng/ml ED50.
Purity: > 95.0% as determined by analysis by SDS-PAGE.