C003P: Adalimumab Biosimilar, TNF alpha Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody adalimumab biosimilar specifically binds to the human TNF alpha.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by adalimumab.BP005287: Biotinylated Human TNF alpha Protein with the C-His-Avi Tag
Source: The recombinant Biotinylated Human TNF alpha Protein, (amino acids Val77-Leu233) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human TNF R2 protein with the C-His-Avi tag at 0.5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Biotinylated Human TNF alpha protein with the C-His tag with the EC50 of 5.1 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.MB088-450-20: Safectine RU50 DNA Transfection Kit
For DNA transfection to mammalian cells.
1. Simplest transfection protocol - ready to use, just mix with DNA and vortex;
2. Superior transfection efficiency;
3. Effective for both adherent and suspension cells;
4. Minimal cytotoxicity;
5. Change of cell culture media after transfection is recommended but not required;
6. Highly reproducible results;
7. Product stable at 4°C and at -20°C.BP005407: Human TNF alpha Protein with the C-His-Avi Tag
Source: The recombinant Human TNF alpha Protein, (amino acids Val77-Leu233) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human TNF alpha protein with the C-His-Avi tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human TNFR2 protein with the C-mFc tag with the EC50 of 45.8 ng/ml determined by ELISA (QC Test). The affinity constant of 1.62 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.C003: Humira Biosimilar Stable Cell Line (CHO)
The yield of Humira biosimilar from the CHO stable cell line was above 2.0 g/L in a 50 liter manufacturing.
C011P: Infliximab Biosimilar, TNF alpha Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody Infliximab biosimilar specifically binds to the human TNF alpha.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by Infliximab.C011: Remicade Biosimilar Stable Cell Line (CHO)
The yield of Remicade biosimilar from the CHO stable cell line was above 1.5 g/L in flask.
BP000123-C082: Recombinant Rabbit Tumor Necrosis Factor alpha (TNFα) Protein
Source: E. coli-derived.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).BP000123-C036: Recombinant Human Tumor Necrosis Factor-alpha (TNFα) Mutant Protein
Source: E. coli-derived.
The ED50 as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D is less than 0.01 ng/ml. Specific Activity of 1.0 x 10^8 IU/mg.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 EU/ug).BP000123-CYT-008: Recombinant Rabbit Tumor Necrosis Factor α (TNFα) Protein
Source: E. coli-derived.
The ED50 as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D is less than 0.03 ug/ml, corresponding to a Specific Activity of 30,000,000 IU/mg.
Purity: > 95% by RP-HPLC and SDS-PAGE.