Fast return: 8 days for standard site-directed mutagenesis;
Point mutations, deletions, or insertions of several amino acids can be performed in a single mutagenesis reaction. The same price is charged for incorporating several mutations, as long as the changes are localized and can be introduced in a single reaction. The same price is charged no matter the size of gene is.Random mutagenesis based on PCR and other methods.
The most comprehensive murine hybridoma generation for therapeutic antibody services:
Genetic background: white, black, immunodeficiency, knock-out, and humanized mice; rat; hamster;
Antigens: proteins, peptides, DNA, cells expressing certain proteins.
All are done in US.
The most comprehensive rabbit monoclonal antibody production services: custom production of rabbit monoclonal antibodies against non-modified, phospho-specific, methylation-specific, and acetylation-specific peptides and proteins; rabbit monoclonal antibodies for ELISA, Western blot, IP, IF, ICC, and IHC applications. Syd Labs team has successfully developed a large number of high specificity and high affinity rabbit monoclonal antibodies against a wide range of difficult targets such as small molecules, antibody idiotype, and antigens non-immunogenic in murine, camel or Ilama.
Fast turnaround: 18 weeks once the antigen is available.Syd Labs has successfully developed human and monkey monoclonal antibodies using antigen specific single B cell-based antibody generation technologies. After detection and isolation of antigen specific memory B cells by flow cytometry-based single B cell sorting, the antibody variable regions (VH and VL) from single or clonal B cells are cloned and sequenced. Recombinant rabbit monoclonal antibodies are produced, purified, and tested for various applications, such as drug development and diagnostics.
Fast turnaround: 8-10 weeks once the polyclonal sera, PBMC, and antigen is available.Our Ad5-RGD and Ad5/35 adenovirus production services include: 1) construction of an Ad5-RGD and Ad5/35 adenovirus vector for expression or silencing of a gene; 2) generation of Ad5-RGD and Ad5/35 adenovirus; 3) amplification and purification of Ad5-RGD and Ad5/35 adenovirus.
Our adenovirus production team has constructed, amplified, and purified thousands of adenoviruses for worldwide clients in more than a decade. An improved technology is used to simplify and accelerate construction of adenoviral vectors for researchers studying gene expression or gene silencing in mammalian systems.
Fast turnaround: 2 weeks.Our retrovirus production services include: 1) construction of a retrovirus plasmid vector for expression or silencing of a gene; 2) retrovirus packaging; 3) retrovirus purification; 4) retrovirus titration.
We have always optimized our retrovirus production systems, including retrovirus plasmid construction and low endotoxin plasmid preparation, host cells for retrovirus packaging, cell culture medium and retrovirus packaging process, small and large scale retrovirus purification process.
Fast turnaround: 2-3 weeks.Our complete custom Adeno-associated Virus (AAV) production services include: 1) AAV plasmid vector construction; 2) AAV packaging; 3) AAV purification by iodixanol or column chromatography; 4) AAV titering by qPCR.
We have always optimized our AAV production systems, including AAV plasmid vector design and construction and low endotoxin plasmid preparation, host cells for AAV packaging, cell culture medium and AAV packaging process, small and large scale AAV purification process.
Fast turnaround: 2-3 weeks.Our complete custom lentivirus production services include: 1) lentivirus vector construction for expression or silencing of a gene; 2) lentivirus packaging; 3) lentivirus purification; 4) lentivirus titering.
We have always optimized our lentivirus production systems, including lentivirus plasmid construction and low endotoxin plasmid preparation, host cells for lentivirus packaging, cell culture medium and lentivirus packaging process, small and large scale lentivirus purification process.
Fast turnaround: 2-3 weeks.Experienced scientists working on antibody and cell line development services for decades. >90% success rate of stable cell line generation.
Stable cell lines developed with our proprietary recombinant antibody expression system with multiple selectable markers is very productive in expressing target proteins.
Fast turnaround:
Basic service: 7-8 weeks.
Premium service: 12-14 weeks.
Pool cells: 6 weeks.