BP000221-CYT-530: Recombinant Pufferfish Leptin
Source: E. Coli-derived.
Biological active as evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. The affinity of human leptin receptors is considerably lower campared to mammalian leptins.
Purity > 99.0% by reducing SDS?PAGE and SEC-HPLC.APIM050150: GDC-0941 (FREE BASE)
CAS No.: 957054-30-7.
Purity: >99% (HPLC at 214 and 254 nm).
QC: LC/MS, 1HNMR, HPLC.
Solubility: Soluble in DMSO.APIM050174: INCB018424 (RUXOLITINIB)
CAS No.: 941678-49-5.
Purity: Refer to Certificate of Analysis, batch-specific.
QC: HPLC, 1HNMR, Chiral HPLC, and Quantitative Elemental Analysis.
Solubility: Water, >50 mM.APIM050298: DOCETAXEL
CAS No.: 114977-28-5.
Purity: >99.5% (by HPLC).
QC: HPLC, NMR, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO, Alcohols, Acetone, insoluble in water.C032P: Tocilizumab Biosimilar, Anti-Human IL-6R Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade tocilizumab biosimilar specifically binds to the human interleukin-6 receptor (IL-6R).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by tocilizumab.BP4125: In Vivo Grade Recombinant Human IgG3 Fc protein (hIgG3 Fc)
Source: mammalian cell-derived.
Purity: >95% by SDS-PAGE under reducing conditions
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.
Recombinant human IgG1 Fc protein mutants available including hIgG1 Fc C103S; hIgG1 Fc D265A; hIgG1 Fc R214K; hIgG1 Fc R214K/N297A; hIgG1 Fc L234A/L235A; hIgG1 Fc L234F/L235E/P331S; hIgG1 Fc L235A/G237A. Recombinant human IgG1 isotype control antibody and mutants are available. Biotinylated hIgG1 Fc, and hIgG1 Fc with Avi-, His-, and Flag-tags are also available.C034P: Secukinumab Biosimilar, Human IL17A Monoclonal Antibody
Recombinant fully human IgG1 monoclonal antibody.
Specificity/Sensitivity: The monoclonal antibody Secukinumab biosimilar specifically binds to the human IL17A.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by Secukinumab.