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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal TNC Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Troponin is a fundamental regulatory protein of striated muscle contraction, and together with tropomyosin, is positioned on the actin filament. Troponin has 3 subunits: TnI- the inhibitor of actomyosin ATPase; TnT- contains the binding site for tropomyosin; and TnC- the protein encoded by the TNNC1 gene. The binding of calcium to TnC stops the inhibitory action of TnI, consequently allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in the TNNC1 gene are linked to cardiomyopathy dilated type 1Z.
BP001865-PRO-959: Recombinant Human Cardiac Trponin C His (TNC) Protein
Source: E. coli-derived.
Recombinant Human Troponin-C His is a single, non-glycosylated polypeptide chain containing 181 amino acids (1-161) and having a molecular mass of 20.5 kDa. Intein is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity: > 95% as determined by SDS-PAGE.
Formulation: The Troponin-C solution (1 ug/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 0.1 M NaCl and 10% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other TNC Proteins:
Recombinant Human Cardiac Trponin C Protein
Recombinant Human Cardiac Troponin I Protein
Rabbit Skeletal Muscle Troponin-C Protein
TNC Antibodies:
TNC Polyclonal Antibody
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