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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal TNC Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Troponin is a fundamental regulatory protein of striated muscle contraction, and together with tropomyosin, is positioned on the actin filament. Troponin has 3 subunits: TnI- the inhibitor of actomyosin ATPase; TnT- contains the binding site for tropomyosin; and TnC- the protein encoded by the TNNC1 gene. The binding of calcium to TnC stops the inhibitory action of TnI, consequently allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in the TNNC1 gene are linked to cardiomyopathy dilated type 1Z.
BP001865-PRO-323: Rabbit Skeletal Muscle Troponin-C (TNC) Protein
Source: Rabbit Skeletal Muscle-derived.
Rabbit Skeletal Muscle Troponin-C is a single, glycosylated, polypeptide chain having a molecular mass of 18,096 Dalton. Troponin-C is one of three subunits that form the Troponin complex of striated muscle thin filaments. Skeletal muscle Troponin-C is purified using a combination of ion-exchange and affinity chromatography steps.
Purity: > 95.0% as determined by SDS-PAGE.
Formulation: Lyophilized from a solution (23.2 mg/ml) containing 150 mM sodium chloride, 10 mM sodium phosphate and 0.05% sodium azide, (pH 7.2).
Reconstitution: It is recommended to reconstitute the lyophilized Troponin C in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other TNC Proteins:
Recombinant Human Cardiac Trponin C His Protein
Recombinant Human Cardiac Trponin C Protein
Recombinant Human Cardiac Troponin I Protein
TNC Antibodies:
TNC Polyclonal Antibody
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