Name: Myelin Basic Protein Antibody
Brand: Syd Labs
SKU: PA000133-P0495
Price: 326.00 USD
Availability: InStock
Rating: 5 (10 reviews)

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PA000133-P0495

Myelin Basic Protein MBP Polyclonal Antibody

100 ug

326.00

Description

Background
Myelin basic protein (MBP) is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the central nervous system and the peripheral nervous system, respectively. It is most abundant in hemopoietic system and contains seven exons distributed over 32-34 kb. MBP isolated from MS brain may differ in charge microheterogeneity which would affect antigenic determinants. MBP is mapped to chromosome 18q22-23. Failure in this gene expression would be correlated in the central white matter with extrapyramidal system degeneration signs. Moreover, it is a candidate autoantigen in the disease multiple sclerosis.

PA000133-P0495: Myelin Basic Protein MBP Polyclonal Antibody

Form of Antibody: 250 umg/mL in 0.1 N Tris-acetate, pH7.0, 0.1% NaN3.
Immunogen: Bovine myelin basic protein (MBP)
Purification: Affinity purified with pan MBP peptide (PRTPPPSQGKGRGL) on Agarose
Specificity/Sensitivity: Recognize 20 kd bovine myelin basic proteins. May cross-react with other isoforms of other mammalian myelin basic proteins as the affinity binding-sequence is identical.
Applications: ELISA, WB, IP.

Storage/Stability: Stable for 1 year at -20°C and 3 months at -20°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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