BP000221-C067: Recombinant Human Leptin (LEP) Protein
Source: E. coli-derived.
The ED50 of Recombinant Human Leptin as determined by dose-dependent cell proliferation assay using human Leptin R transfected BaF3 mouse proB cells was found to be approximately 0.42 ug/ml.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).BP000221-CYT-227: Recombinant Rat Leptin (LEP) Protein
Source: E. Coli-derived.
Biological activity of Leptin Rat is evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor.
Purity: > 95.0% by reducing SDS-PAGE and SEC-HPLC.BP000221-CYT-228: Recombinant Human Leptin (LEP) Protein
Source: E. Coli-derived.
Biological Activity is evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor.
Purity: > 95.0% by reducing SDS-PAGE and SEC-HPLC.BP000221-CYT-502: Recombinant Bovine Leptin (LEP) Protein
Source: E. Coli-derived.
Biological active as evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor.
Purity: > 95.0% by reducing SDS-PAGE and SEC-HPLC.BP000221-CYT-351: Recombinant Mouse Leptin (LEP) Protein
Source: E. Coli-derived.
Biological activity of Mouse Leptin is performed in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 ug Leptin/gram body weight for a period of 14 days. Significant effects on body weight , food consumption, and plasma glucose levels were observed to saline-treated controls.
Purity: > 95.0% by reducing SDS?PAGE and SEC-HPLC.BP000221-CYT-503: Recombinant Porcine Leptin (LEP) Protein
Source: E. Coli-derived.
Biological active as evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor.
Purity: > 98.0% by Gel filtration analysis and SDS-PAGE.BP000221-CYT-504: Recombinant Horse Leptin (LEP) Protein
Source: E. Coli-derived.
Biological active as evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor.
Purity: > 95.0% by reducing SDS?PAGE and SEC-HPLC.BP000221-CYT-505: Recombinant Chicken Leptin (LEP) Protein
Source: E. Coli-derived.
Biological active as evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Its activity is however 5-10 fold lower as compared to mammalian leptins.
Purity: > 95.0% by reducing SDS?PAGE and SEC-HPLC.BP000221-CYT-591: Recombinant Mouse Pegylated Leptin
Source: E. Coli-derived.
Pegylated mouse Leptin is capable of stimulatng proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Pegylated mouse Leptin in vitro activity is only slightly lower than the non-pegylated antagonist but in vivo it has profound weight reducing effect (as compared to the non-pegylated leptin), resulting mainly from reduced food intake.
Purity > 99.0% by Gel-Filtration and SDS?PAGE.BP000221-CYT-239: Recombinant Ovine Leptin (LEP) Protein
Source: E. Coli-derived.
Biological active as evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor.
Purity: > 95.0% by SEC-HPLC and SDS-PAGE