PA007381.r2b: In vivo Grade Recombinant Anti-mouse CD8a Monoclonal Antibody, Rat IgG2b Kappa (Clone: YTS 105.18)

The in vivo grade recombinant anti-mouse CD8a rat IgG2b monoclonal antibody was produced in mammalian cells. 
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: YTS 105.18) specifically binds to mouse CD8a.
Applications: Western blot, immunohistochemistry (IHC), Flow Cytometry (FC), and in vivo CD8+ T cell depletion.

PA007276.r2a: In vivo Grade Recombinant Anti-mouse CD137 (TNFRSF9 or 4-1BB) Monoclonal Antibody, Rat IgG2a Kappa (Clone: 3H3)

Recombinant rat IgG2a Monoclonal Antibody. 
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: 3H3) specifically binds to the mouse 4-1BB protein.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse 4-1BB protein.

PA007575.m1:In Vivo Grade Recombinant Anti-human EGFR Monoclonal Antibody (Clone: 225), Mouse IgG1 Kappa

Recombinant Mouse IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: 225) specifically binds to human EGFR.
Applications:ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human EGFR protein.

C110P: Tanezumab Biosimilar, NGF Monoclonal Antibody

Recombinant Humanized IgG2 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade tanezumab biosimilar specifically binds to the NGF protein.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by tanezumab.

C108P: Rovalpituzumab Biosimilar, DLL3 Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The research grade rovalpituzumab biosimilar specifically binds to the DLL3 protein.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by rovalpituzumab.

BP003399: Mouse Her3/ErbB3 Protein with the C-His Tag

Source: The recombinant Mouse Her3/ErbB3 Protein, (amino acids Ser20-His641) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Mouse Her3 protein with the C-His tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human NRG1 Beta 1 protein with the C-hFc tag with the EC50 of 47.8 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005130: Human Her4/ErbB4 Protein with the C-hFc Tag

Source: The recombinant Human Her4/ErbB4 Protein, (amino acids Gln26-Pro651) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human Her4 protein with the C-hFc tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human NRG1 Beta 1 protein with the C-hFc tag with the EC50 of 94.6 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005016: Human Her4/ErbB4 Protein with the C-His-Avi Tag

Source: The recombinant Human Her4/ErbB4 Protein, (amino acids Gln26-Pro651) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human Her4 protein with the C-His-Avi tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human NRG1 Beta 1 protein with the C-hFc tag with the EC50 of 34.7 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005496: Human Her3/ErbB3 Protein with the C-hFc Tag

Source: The recombinant Human Her3/ErbB3 Protein, (amino acids Ser20-Thr643) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human Her3 protein with the C-hFc tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Anti-Her3 Antibody protein with the C- hFc tag with the EC50 of 12.8 ng/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005372: Human Her3/ErbB3 Protein with the C-His-Avi Tag

Source: The recombinant Human Her3/ErbB3 Protein, (amino acids Ser20-Thr643) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human Her3 protein with the C-His-Avi tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-Her3 Antibody protein with the C-hFc tag with the EC50 of 5.7 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003168: FITC-Labeled Human Her3/ErbB3 Protein with the C-His-Avi Tag

Source: The recombinant FITC-Labeled Human Her3/ErbB3 Protein, (amino acids Ser20-Thr643) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant FITC-Labeled Human Her3 protein with the C-His-Avi tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human NRG1 Beta 1 protein with the C-hFc tag with the EC50 of 23.6 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003905: Cynomolgus/Rhesus macaque Her3 Protein with the C-His Tag

Source: The recombinant Cynomolgus/Rhesus macaque Her3 Protein, (amino acids Ser20-His641) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus/Rhesus macaque Her3 protein with the C-His tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-Her3 Antibody protein with the C-hFc tag with the EC50 of 20.1 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.