BP003358: Biotinylated Human FLT3/Flk-2 Protein with the C-His-Avi Tag
Source: The recombinant Biotinylated Human FLT3/Flk-2 Protein, (amino acids Asn27-Asn541) fused with a His-Avi tag at the C-terminus, was produced in CHO cells.
Activity: Immobilized recombinant Human FLT3 Ligand protein with the C-His-Avi tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human FLT3 protein with the C-His tag with the EC50 of 0.26 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003724: Cynomolgus FLT3/Flk-2 Protein with the C-hFc Tag
Source: The recombinant Cynomolgus FLT3/Flk-2 Protein, (amino acids Gln28-Ser541) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human FLT3 Ligand protein with the C-hFc tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Cynomolgus FLT3 protein with the C-hFc tag with the EC50 of 18.2 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP000045-360: Recombinant Mouse FLT3L
Source: CHO cell-derived.
Activity: Effective in generating BM-derived DC precursors (30-100 ug/ml in vitro; 10 ug per animal daily in vivo).
Purity >90% by SDS-PAGE.
Endotoxin Level: Less than 1 EU/ug of protein as determined by LAL method.BP000045-CA82: Recombinant Human Flt3 Ligand
Source: HEK 293-derived.
Purity > 95%, by reducing SDS-PAGE and SEC-HPLC.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug).BP000045-CYT-340: Recombinant Mouse Flt3 Ligand
Source: E. coli-derived.
The ED50, calculated by the dose-dependent proliferation of mouse AML5 cells is less than 7.0 ug/ml.
Purity > 95%, by SDS-PAGE and RP-HPLC.BP000045-CYT-409: Recombinant Human Flt3 Ligand, Sf9
Source: Baculovirus Sf9 cells-derived.
The ED50, calculated by the dose-dependant stimulation of the proliferation of human MUTZ-2cells is < 3.0 ug/ml.
Purity > 95%, by SDS-PAGE and RP-HPLC.BP000045-CYT-706: Recombinant Human Flt3 Ligand, HEK derived
Source: HEK293 (Human Embryonic Kidney cell line)-derived.
The ED50 as determined by the dose dependent proliferation of human OCI-AML5 cells is 0.5 to 1.0 ug/ml (Specific Activity: 2.0 x 1,000,000?.0 x 1,000,000 units/mg).
Purity > 95%, by SDS-PAGE and RP-HPLC.BP000045-CYT-157: Recombinant Rhesus Macaque Flt3 Ligand
Source: E. coli-derived.
The ED50 as calculated by the dose-dependant stimulation of the proliferation of human AML5 cells is less than 1.0 ng/ml, corresponding to a specific activity of 1,000,000 IU/mg.
Purity: > 97.0% as determined by SDS-PAGE.BP000045-CYT-331: Recombinant Human Flt3 Ligand
Source: E. coli-derived.
The ED50 range=0.5-1.0 ng/ml corresponding to a specific activity of 1-2 MUnits/mg, calculated by the dose-dependant stimulation of the proliferation of human OCMI-AML5 cells.
Purity > 95%, by SDS-PAGE and RP-HPLC.BP000046-350: Mouse Flt3L Fc fusion protein
Source: CHO cell-derived.
Activity: Effective in generating BM-derived DC precursors (3-10 ug/ml in vitro, 10 ug per animal every 3-4 days in vivo); binds to bone marrow derived dendritic cells as shown in flow cytometry.
About 10 times more potent than native Flt3L in vitro and in vivo.
Better pharmacokinetics than native Flt3L in vivo.
Purity >90% by SDS-PAGE.
Endotoxin Level: Less than 1 EU/ug of protein as determined by LAL method.