C030P: Daratumumab Biosimilar, CD38 Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade daratumumab biosimilar specifically binds to the human CD38 protein, causing cells to apoptose via antibody-dependent cellular cytotoxicity, complement-dependent cytotoxicity, inhibition of mitochondrial transfer or antibody-dependent cellular phagocytosis.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by daratumumab.BP004799: Human BST1 Protein with the C-His Tag
Source: The recombinant Human BST1 Protein, (amino acids Gly29-Ala293) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human BST1 protein with the C-His tag at 0.5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-BST1 Antibody protein with the C-hFc tag with the EC50 of 8.4 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.C068P: Isatuximab Biosimilar, CD38 Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade isatuximab biosimilar specifically binds to the human CD38 proteins.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by isatuximab.BP004903: Mouse BST1 Protein with the C-His Tag
Source: The recombinant Mouse BST1 Protein, (amino acids Ala25-Ser286) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.