Biologics production stable cell line development services utilize advanced technology platforms to generate cell lines expressing the target gene at very high levels for the manufacturing of recombinant proteins and antibodies.

- Performed under GLP; manufactured product may be used in FDA Nonclinical Laboratory Studies.
- Parental cell line is cGMP banked with certification.
- Set licensing fee arrangement for commercial production license.
- Cell lineage history of the cell line and testing details facilitate IND filing.

BP003132: Biotinylated Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer Protein with the C-His-Avi Tag

Source: The recombinant Biotinylated Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer Protein, (amino acids Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GLYDGMEHL peptide) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003092: Human Peptide Ready HLA-B*07:02&B2M Monomer Protein with the C-His-Avi Tag

Source: The recombinant Human Peptide Ready HLA-B*07:02&B2M Monomer Protein, (amino acids Gly25-Val309(HLA-B*07:02) & Ile21-Met119(B2M)) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human Peptide Ready HLA-B*07:02&B2M Monomer protein with the C-His-Avi tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-HLA class I (W6/32) Antibody protein with the C-hFc tag with the EC50 of 4.9 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003271: Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein with the C-His-Avi Tag

Source: The recombinant Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein, (amino acids His23-Pro296(Qa-1b), Ile21-Met119(B2M) and AMAPRTLLL peptide) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003270: Mouse H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein with the C-His-Avi Tag

Source: The recombinant Mouse H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, (amino acids His24-Pro297, Ile21-Met119(B2M) and SIINFEKL peptide) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003985: Cynomolgus MICA Protein with the C-His Tag

Source: The recombinant Cynomolgus MICA Protein, (amino acids Glu1-Trp284) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus MICA protein with the C-His tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human NKG2D protein with the C-hFc tag with the EC50 of 0.14 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003564: Human MICA Protein with the C-hFc Tag

Source: The recombinant Human MICA Protein, (amino acids Glu24-Gln308) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human NKG2D protein with the C-hFc tag at 5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Human MICA protein with the C-hFc tag with the EC50 of 3.2 ng/ml determined by ELISA (QC Test). The affinity constant of 0.36 uM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005512: Human MICA Protein with the C-His-Avi Tag

Source: The recombinant Human MICA Protein, (amino acids Glu24-Gln308) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human MICA protein with the C-His-Avi tag at 5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Human NKG2D protein with the C-hFc tag with the EC50 of 0.81 ug/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003562: Human MICB Protein with the C-hFc Tag

Source: The recombinant Human MICB Protein, (amino acids Ala23-Gly298) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human MICB protein with the C-hFc tag at 2 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Biotinylated Anti-MICB Antibody protein with the C-hFc tag with the EC50 of 26.6 ng/ml determined by ELISA (QC Test). The affinity constant of 95.15 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005513: Human MICB Protein with the C-His-Avi Tag

Source: The recombinant Human MICB Protein, (amino acids Ala23-Gly298) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human MICB protein with the C-His-Avi tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-MICB Antibody protein with the C-hFc tag with the EC50 of 42.4 ng/ml determined by ELISA. The affinity constant of 83.31 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003616: Human MICA alpha 3 Protein with the N-mFc Tag

Source: The recombinant Human MICA alpha 3 Protein, (amino acids Arg105-Ser200) fused with a mFc tag at the N-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human MICA alpha 3 protein with the N-mFc tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-MICA Antibody protein with the N-hFc tag with the EC50 of 0.10 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

PA000635-A0604: ACK1 (Phospho-Tyr284) Polyclonal Antibody

Rabbit Polyclonal Antibody;
Applications: WB, IHC, IF, ELISA;
Reactivity: Human, Mouse, Rat.