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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal BCL10 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
BCL10 holds a caspase recruitment domain (CARD), and is known as an inducer of apoptosis and as NF-kappaB activator. BCL10 cooperates with other CARD domain containing proteins such as CARD9, 10, 11 and 14, which operates as upstream regulators in NF-kappaB signaling. BCL10 is known to create a complex with MALT1, a protein encoded by another gene and is translocated in MALT lymphoma. MALT1 and BCL10 protein synergize the activation of NF-kappaB, and the deregulation of either of them facilitates the same pathogenetic process which leads to the malignancy.
BP001833-PRO-1058: Recombinant Human B-cell CLL/Lymphoma 10 (BCL10) Protein
Source: E. coli-derived.
Recombinant Human BCL10 is a single polypeptide chain containing 257 amino acids (1-233) and having a molecular mass of 28.8 kDa. BCL10 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Predicted molecular mass of 28.8 kDa.
Purity: > 85% as determined by SDS-PAGE.
Formulation: The BCL10 solution (1 ug/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 50 mM Nacl, 1 mM DTT and 10% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
BCL10 Antibodies:
BCL10 Polyclonal Antibody
BCL10 Polyclonal Antibody
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