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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Recombinant rat IgG2a isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Recombinant Rat IgG2a Monoclonal Antibody.
Clone: M18/2.a.12.7.
Isotype: Rat IgG2a Kappa.
Source: The anti-mouse CD18 monoclonal antibody (clone: M18/2.a.12.7) was produced in mammalian cells.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: M18/2.a.12.7) specifically binds to mouse CD18.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD18 protein.
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin: < 1 EU per 1 mg of the protein by the LAL method.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.
Shipping: The in vivo grade recombinant anti-mouse CD18 monoclonal antibody of clone M18/2.a.12.7 is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month from date of receipt, 2 to 8°C as supplied.
Anti-CD18 monoclonal antibody slows reinnervation after nerve injury
Cotman JD, et al. J Hand Surg Am. 2003 Nov;28(6):1021-7. doi: 10.1016/j.jhsa.2003.09.008. PMID: 14568010
Rats were treated with anti-mouse CD18 antibody (M18/2 clone) intraperitoneally to block leukocyte adhesion in vivo. Anti-mouse CD18 administration delayed axonal regeneration in the sciatic nerve model. In vivo CD18 blockade reduced macrophage infiltration at the injury site. Functional recovery assessed by walking track analysis was slowed post-anti-mouse CD18. Nerve histology showed decreased myelin formation in anti-mouse CD18 cohorts.
Tags: anti-mouse CD18 M18/2.a.12.7; anti-mouse CD18 M18/2.a.12.7 in vivo
Anti-CD18 monoclonal antibody slows reinnervation after nerve injury
Cotman JD, et al. J Hand Surg Am. 2003 Nov;28(6):1021-7. doi: 10.1016/j.jhsa.2003.09.008. PMID: 14568010
Rats were treated with anti-mouse CD18 antibody (M18/2 clone) intraperitoneally to block leukocyte adhesion in vivo. Anti-mouse CD18 administration delayed axonal regeneration in the sciatic nerve model. In vivo CD18 blockade reduced macrophage infiltration at the injury site. Functional recovery assessed by walking track analysis was slowed post-anti-mouse CD18. Nerve histology showed decreased myelin formation in anti-mouse CD18 cohorts.
Tags: anti-mouse CD18 M18/2.a.12.7 antibody in mouse tumor model; bioactivity of anti-mouse CD18 M18/2.a.12.7
Anti-CD18 monoclonal antibody slows reinnervation after nerve injury
Cotman JD, et al. J Hand Surg Am. 2003 Nov;28(6):1021-7. doi: 10.1016/j.jhsa.2003.09.008. PMID: 14568010
Rats were treated with anti-mouse CD18 antibody (M18/2 clone) intraperitoneally to block leukocyte adhesion in vivo. Anti-mouse CD18 administration delayed axonal regeneration in the sciatic nerve model. In vivo CD18 blockade reduced macrophage infiltration at the injury site. Functional recovery assessed by walking track analysis was slowed post-anti-mouse CD18. Nerve histology showed decreased myelin formation in anti-mouse CD18 cohorts.
Tags: anti-mouse CD18 M18/2.a.12.7 of low endotoxin; anti-mouse CD18 M18/2.a.12.7 antibody of low endotoxin
Anti-CD18 monoclonal antibody slows reinnervation after nerve injury
Cotman JD, et al. J Hand Surg Am. 2003 Nov;28(6):1021-7. doi: 10.1016/j.jhsa.2003.09.008. PMID: 14568010
Rats were treated with anti-mouse CD18 antibody (M18/2 clone) intraperitoneally to block leukocyte adhesion in vivo. Anti-mouse CD18 administration delayed axonal regeneration in the sciatic nerve model. In vivo CD18 blockade reduced macrophage infiltration at the injury site. Functional recovery assessed by walking track analysis was slowed post-anti-mouse CD18. Nerve histology showed decreased myelin formation in anti-mouse CD18 cohorts.
Tags: anti-mouse CD18 antibody (M18/2.a.12.7); anti-mouse CD18 M18/2.a.12.7
Anti-CD18 monoclonal antibody slows reinnervation after nerve injury
Cotman JD, et al. J Hand Surg Am. 2003 Nov;28(6):1021-7. doi: 10.1016/j.jhsa.2003.09.008. PMID: 14568010
Rats were treated with anti-mouse CD18 antibody (M18/2 clone) intraperitoneally to block leukocyte adhesion in vivo. Anti-mouse CD18 administration delayed axonal regeneration in the sciatic nerve model. In vivo CD18 blockade reduced macrophage infiltration at the injury site. Functional recovery assessed by walking track analysis was slowed post-anti-mouse CD18. Nerve histology showed decreased myelin formation in anti-mouse CD18 cohorts.
Tags: clone M18/2.a.12.7 of anti-mouse CD18 mAb; M18/2.a.12.7 anti-mouse CD18 antibody
For more references about anti-mouse CD18 antibody (Clone: M18/2.a.12.7), please contact our scientific support team with message@sydlabs.com.
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