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Vim Protein

Vimentin, FLJ36605

Catalog No. Product Name Size List Price (US$) Quantity
BP001898-PRO-734 Recombinant Human Vimentin, GST Tag Protein 2 ug 175.00
BP001898-PRO-734 Recombinant Human Vimentin, GST Tag Protein 5 ug 270.00
BP001898-PRO-734 Recombinant Human Vimentin, GST Tag Protein 10 ug 490.00
Description

Introduction
Vimentin expression in human malignant glioma cells depends on cellular density, algorithms of drug delivery and chemo/radio treatment. Vimentin and detyrosinated microtubules provide structural support for the extensive microtentacles observed in detached tumor cells and a mechanism to promote successful metastatic spread. Primary colorectal carcinomas display aberrant expression of vimentin, and have activated Notch and TGFbeta signaling pathways. Vimentin is a strong arterial substrate for transglutaminases. Transglutaminase-mediated vimentin dimerization results in a novel unifying pathway by which vasodilatory and remodeling responses may be regulated. Ablation of vimentin expression inhibits migration and invasion of colon and breast cancer cell lines. Vimentin is the main intermediate filament protein in mesenchymal cells and is therefore of value in the differential diagnosis of undifferentiated neoplasms.

BP001898-PRO-734: Recombinant Human Vimentin, GST Tag (Vim) Protein

Source: E. coli-derived.
Recombinant Human Vimentin GST Tag full length protein has a molecular weight of 86 kDa (determined by SDS gel elctrophoresis).
Formulation: The Vimentin protein solution contains 50 mM Tris-Acetate, pH-7.5, 1 mM EDTA and 20% Glycerol.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other Vim Proteins:
Recombinant Human Vimentin Protein
Recombinant Human Vimentin Protein

Vim Antibodies:
Biotin Conjugated Vimentin Monoclonal Antibody
Vimentin Polyclonal Antibody
Vimentin Monoclonal Antibody
Vimentin Monoclonal Antibody
Vimentin (Ab-83) Polyclonal Antibody
Vimentin (Ab-56) Polyclonal Antibody
FITC Conjugated Vimentin Monoclonal Antibody

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