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VEGF-C Protein

Vascular Endothelial Growth Factor C, Flt4 Ligand, Flt4-L, Vascular Endothelial Growth Factor-Related Protein, VRP, VEGFC
Catalog No. Product Name Size List Price (US$) Quantity
BP000258-CYT-527 Recombinant Human VEGF-C Related Protein 10 ug 160.00
BP000258-CYT-527 Recombinant Human VEGF-C Related Protein 1 mg 2700.00
Description

Introduction
VEGF-C is a recently discovered VEGF growth factor family member that is most closely related to VEGF-D. Human VEGF-C cDNA encodes a pre-pro-protein of 416 amino acids residues. It is almost identical to the mouse VEGF-C protein. Similar to VEGF-D, VEGF-C has a VEGF homology domain spanning the middle third of the precursor molecule and long N- and C-terminal extensions. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. Recombinant human VEGF-C, lacking the N- and C-terminal extensions and containing only the middle VEGF homology domain, forms primarily non-covalently linked dimers. This protein is a ligand for both VEGFR-2/KDR and VEGFR-3/FLT-4. Since VEGFR-3 is strongly expressed in lymphatic endothelial cells, it has been postulated that VEGF-C is involved in the regulation of the growth and/or differentiation of lymphatic endothelium.

BP000258-CYT-527: Recombinant Human Vascular Endothelial Growth Factor C (VEGF-C) Protein

Source: Sf9, Insect Cells-derived.
Measured by its ability to bind to the VEGFR-3/FLT-4 receptor in the Ba/F3-hVEGFR-3 assay. The ED50 in this assay is about 4 ug/ml corresponding to a Specific Activity of 250,000 IU/mg.
Purity: > 90% by SDS-PAGE and RP-HPLC.
Formulation: Each mg of VEGF-C Human contains 50mg BSA and 1xPBS as buffer.
Reconstitution: It is recommended to reconstitute the lyophilized VEGF-C in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other VEGF-C Proteins:
Recombinant Rat VEGF-C Related Protein
Recombinant Rat VEGF-C (152 a.a) Protein

VEGF-C ELISA Kit:
Human VEGF-C ELISA Kit
 

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