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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal VEGF-C Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
VEGF-C is a recently discovered VEGF growth factor family member that is most closely related to VEGF-D. Human VEGF-C cDNA encodes a pre-pro-protein of 416 amino acids residues. It is almost identical to the mouse VEGF-C protein. Similar to VEGF-D, VEGF-C has a VEGF homology domain spanning the middle third of the precursor molecule and long N- and C-terminal extensions. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. Recombinant human VEGF-C, lacking the N- and C-terminal extensions and containing only the middle VEGF homology domain, forms primarily non-covalently linked dimers. This protein is a ligand for both VEGFR-2/KDR and VEGFR-3/FLT-4. Since VEGFR-3 is strongly expressed in lymphatic endothelial cells, it has been postulated that VEGF-C is involved in the regulation of the growth and/or differentiation of lymphatic endothelium.
BP000258-CYT-262: Recombinant Rat Vascular Endothelial Growth Factor C (VEGF-C) Protein
Source: Sf9, Insect Cells-derived.
The ED50 for this effect is typically 200-300 ug/ml corresponding to a Specific Activity of 3,334-5,000 IU/mg.
Purity: > 90% by SDS-PAGE and RP-HPLC.
Formulation: Each mg of VEGF-C Rat contains 50 mg BSA and PBS as buffer.
Reconstitution: It is recommended to reconstitute the lyophilized Vascular Endothelial Growth Factor C in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other VEGF-C Proteins:
Recombinant Human VEGF-C Related Protein
Recombinant Rat VEGF-C (152 a.a) Protein
VEGF-C ELISA Kit:
Human VEGF-C ELISA Kit
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