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Conditions of optimal VEGI protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial cells. TNFSF15 is also able to regulate the expression of several important genes involved in angiogenesis. These findings are consistent with the view that TNFSF15 functions as an autocrine cytokine to inhibit angiogenesis and stabilize the vasculature.
BP000262-CYT-589: Recombinant Human Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) Protein, His Tag
Source: E. coli-derived.
Recombinant Human VEGI protein fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 201 amino acids (72-251a.a.) and having a molecular mass of 22.7 kDa.
Purity: > 95% by SDS-PAGE.
Formulation: The VEGI solution (1 ug/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 50% glycerol, 1 mM DTT and 0.2 M NaCl.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other TNFSF15 Proteins:
Recombinant Human TNFSF15 Protein
Recombinant Human TNFSF15 Protein
TNFSF15 Antibody:
TNFSF15 Polyclonal Antibody
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