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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal PCNA Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
PCNA is located in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps elevate the processivity of leading strand synthesis during DNA replication. In reaction to DNA damage, PCNA is ubiquitinated and takes part in the RAD6-dependent DNA repair pathway. 2 transcript variants encoding the same protein have been found for PCNA gene. Pseudogenes of this PCNA gene have been described on chromosome 4 and on the X chromosome. PCNA is expressed during late G1- phase, S-phase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA is induced by UV irradiation.
BP002389-PRO-303: Recombinant Human Proliferating Cell Nuclear Antigen, Sf9 (PCNA) Protein
Source: Sf9 insect cells-derived.
Recombinant Human PCNA protein is a glycosylated, polypeptide chain having a molecular mass of 29,794 Dalton. PCNA protein is expressed with a -6xHis tag and purified by proprietary chromatographic techniques.
Applications: Western-Blot with monoclonal anti-hexa-His-tag antibody & Scleroderma patient sera.
Purity: > 95% as determined by SDS-PAGE.
Formulation: Recombinant Human PCNA is supplied in 16 mM HEPES buffer pH-8, 400 mM NaCl, and 20% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other PCNA Proteins:
Recombinant Human Proliferating Cell Nuclear Antigen, GST Tag Protein
Recombinant Human Proliferating Cell Nuclear Antigen Protein
PCNA Antibodies:
PCNA Monoclonal Antibody
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