Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
|---|
Conditions of optimal PAI-1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Plasminogen activator inhibitor 1 (PAI-1) is the primary inhibitor of tissue-type and urokinase-type plasminogen activator, playing a major role in fibrinolysis1-2. PAI-1 is mainly produced by the endothelium, but is also secreted by other tissue types, such as adipose tissue3. It is normally present at low levels in plasma and tissue, but its expression and release increased in various disease states (such as a number of forms of cancer), as well as in obesity and the metabolic syndrome4. PAI-1 is also involved in the pathophysiology of renal, pulmonary, cardiovascular, and metabolic diseases5-8. Elevated local or systemic PAI-1 can also exacerbate such pathologic conditions.
BP000018-ENZ-357: Recombinant Human Plasminogen activator inhibitor 1 (PAI-1) Protein
Source: E. coli-derived.
Recombinant Human Plasminogen activator inhibitor 1 (PAI-1) Protein fused to N-terminal His-Tag produced in E.Coli is a single, non-glycosylated polypeptide chain containing 400 amino acids (24-402) and having a molecular mass of 45 kDa. Recombinant Human Plasminogen activator inhibitor 1 (PAI-1) Protein is purified by proprietary chromatographic techniques.
Purity: > 95.0% by SDS-PAGE.
Formulation: 150 mM Na2HPO4, pH 6.6, 0.5 mM NaCl, 2 mM Glutathione and 0.01% Tween-80.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other PAI-1 Proteins:
Human PAI-1 Protein
Recombinant Human PAI-1 Protein
PAI-1 ELISA Kit:
Human PAI-1 ELISA Kit
Copyright © 2009-2022 sydlabs.com. All rights reserved.
Use of this website means that you have read, understood, and accepted the Syd Labs Privacy Policy and Terms & Conditions.