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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal TAU Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. Tau interacts with tubulin to stabilize microtubules and promotes tubulin assembly into microtubules. The C-terminus of TAU binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau acts as a linker protein. When tau is defective, and no longer stabilize microtubules properly, it can result in dementias such as Alzheimer's disease and other tauopathies.
BP001066-PRO-295: Recombinant Human Microtubule-associated protein tau (MAPT) Protein
Source: E. coli-derived.
Recombinant Human MAPT protein is a single, non-glycosylated polypeptide chain containing 372 amino acids (1-352 a.a.) and having a molecular mass of 38.9 kDa (Real molecular weight on SDS-PAGE will be shift up). The MAPT protein is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Purity: > 85.0% by SDS-PAGE.
Formulation: The MAPT solution (0.5 mg/ml) contains 20 mM Tris-HCl pH-8, 1 mM DTT, 0.2 M NaCl & 10% glycerol.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other MAPT Proteins:
Recombinant Human MAPT Protein
Recombinant Human MAPT 381 a.a. Protein
Recombinant Human MAPT 412 a.a. Protein
Recombinant Human MAPT 383 a.a. Protein
MAPT Antibodies:
MAPT Polyclonal Antibody
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