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MAPT Protein

Microtubule-associated protein tau, Neurofibrillary Tangle Protein, Paired Helical Filament-Tau, PHF-Tau, MAPTL, MTBT1, TAU

Catalog No. Product Name Size List Price (US$) Quantity
BP001066-PRO-210 Recombinant Human MAPT 412 a.a. Protein 5 ug 160.00
BP001066-PRO-210 Recombinant Human MAPT 412 a.a. Protein 50 ug 1200.00
Description

Introduction
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. Tau interacts with tubulin to stabilize microtubules and promotes tubulin assembly into microtubules. The C-terminus of TAU binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau acts as a linker protein. When tau is defective, and no longer stabilize microtubules properly, it can result in dementias such as Alzheimer's disease and other tauopathies.

BP001066-PRO-210: Recombinant Human Microtubule-associated protein tau 412 a.a. (MAPT 412 a.a.) Protein

Source: E. coli-derived.
Recombinant Human MAPT protein fused with a 20 amino acid His tag at N-terminus is a single, non-glycosylated, polypeptide chain containing 432 amino acids (1-412 a.a.) and having a molecular mass of 45.1 kDa (Molecular size on SDS-PAGE will appear higher). The MAPT protein is purified by proprietary chromatographic techniques.
Purity: > 80.0% by SDS-PAGE.
Formulation: The MAPT solution (0.5 mg/ml) contains 20 mM Tris-HCl buffer (pH8.0) and 20% glycerol.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other MAPT Proteins:
Recombinant Human MAPT Protein
Recombinant Human MAPT Protein
Recombinant Human MAPT 383 a.a. Protein
Recombinant Human MAPT 381 a.a. Protein

MAPT Antibodies:
MAPT Polyclonal Antibody

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