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MAPT Protein

Microtubule-associated protein tau, Neurofibrillary Tangle Protein, Paired Helical Filament-Tau, PHF-Tau, MAPTL, MTBT1, TAU

Catalog No. Product Name Size List Price (US$) Quantity
BP001066-C177 Recombinant Human MAPT Protein 10 ug 126.00
BP001066-C177 Recombinant Human MAPT Protein 50 ug 378.00
BP001066-C177 Recombinant Human MAPT Protein 1 mg 2640.00
Description

Introduction
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. Tau interacts with tubulin to stabilize microtubules and promotes tubulin assembly into microtubules. The C-terminus of TAU binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau acts as a linker protein. When tau is defective, and no longer stabilize microtubules properly, it can result in dementias such as Alzheimer's disease and other tauopathies.

BP001066-C177: Recombinant Human Microtubule-associated protein tau (MAPT) Protein

Source: E. coli-derived.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 EU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other MAPT Proteins:
Recombinant Human MAPT Protein
Recombinant Human MAPT 412 a.a. Protein
Recombinant Human MAPT 383 a.a. Protein
Recombinant Human MAPT 381 a.a. Protein

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