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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal Leptin Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
A 16-kDa peptide hormone secreted from white adipocytes and implicated in the regulation of food intake and energy balance. Leptin provides the key afferent signal from fat cells in the feedback system that controls body fat stores.
BP000221-CYT-592: Recombinant Rat Pegylated Leptin (LEP) Protein
Source: E.Coli-derived.
A single, non-glycosylated, polypeptide chain containing 147 amino acids and an additional Ala at N-terminus having a molecular mass of 35.6 kDa (with 20 kDa PEG) as determined by mass spectometry.
Pegylated Rat Leptin is capable of stimulatng proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Its in vitro activity is only slightly lower than the non-pegylated antagonist but in vivo it has profound weight reducing effect (as compared to the non-pegylated leptin), resulting mainly from reduced food intake.
Purity > 99.0% by reducing SDS?-PAGE and SEC-HPLC.
Formulation: The protein was lyophilized from a concentrated (0.65 mg/ml) solution with 0.003 mM NaHCO3.
Reconstitution: It is recommended to reconstitute the lyophilized pegylated Rat Leptin in sterile 0.4% NaHCO3 adjusted to pH-8.5, not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other LEP Proteins:
Recombinant Salamander LEP Protein
Recombinant Rat Leptin Protein
Recombinant Rabbit LEP Protein
Recombinant Porcine LEP Protein
Recombinant Ovine Leptin Protein
Recombinant Mouse LEP Protein
Recombinant Human Leptin Protein, His Tag
Recombinant Human Leptin Protein
Recombinant Human Leptin Protein
Recombinant Human LEP Protein
Recombinant Horse LEP Protein
Recombinant Dog LEP Protein
Recombinant Chicken LEP Protein
Recombinant Bovine Leptin Protein
Recombinant Chicken LEP Protein
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