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LEP Protein

Leptin, Obese Protein, Obesity Factor, OB, OBS

Catalog No. Product Name Size List Price (US$) Quantity
BP000221-CYT-287 Recombinant Human Leptin Protein, His Tag 25 ug 160.00
BP000221-CYT-287 Recombinant Human Leptin Protein, His Tag 1 mg 2400.00
Description

Introduction
Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. Animal models have revealed the influence of Leptin in reducing body weight and regulating blood glucose level. When mutations are introduced in obese gene, mice with impaired function of leptin are massively obese and in high risk of diabetes. Leptin deficiency reduces metablic rate. Leptin deficient mice are less active and with lower body temperature than normal animals. Human Leptin shares approximately 84% sequence identity with the mouse protein. Human Leptin consists of 167 amino acid residue including a 21 amino acid residue signal sequence and 146 amino acid residue mature protein sequence.

BP000221-CYT-287: Recombinant Human Leptin (LEP) Protein, His Tag

Source: E. Coli-derived.
Purity: > 90.0% by RP-HPLC and SDS-PAGE.
Formulation:The protein was lyophilized from a concentrated (1 mg/ml) solution with 1X PBS, 0.1% SDS and 1 mM DTT.
Reconstitution: The lyophilized Leptin is very soluble in water and most aqueous buffers below and above the isoelectric point.
Applications: Positive control for Western blot; Antibody production; Protein assay.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-?thaw cycles.
12 months from date of receipt, -20 to -?70? as supplied.

Other LEP Proteins:
Recombinant Salamander LEP Protein
Recombinant Rat Leptin Protein
Recombinant Porcine LEP Protein
Recombinant Mouse LEP Protein
Recombinant Human Leptin Protein
Recombinant Human Leptin Protein
Recombinant Human LEP Protein
Recombinant Horse LEP Protein
Recombinant Dog LEP Protein
Recombinant Chicken LEP Protein
Recombinant Bovine Leptin Protein
Recombinant Chicken LEP Protein
Recombinant Rat Pegylated LEP Protein
Recombinant Rabbit LEP Protein
Recombinant Ovine Leptin Protein

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