Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
|---|
Conditions of optimal Leptin Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. Animal models have revealed the influence of Leptin in reducing body weight and regulating blood glucose level. When mutations are introduced in obese gene, mice with impaired function of leptin are massively obese and in high risk of diabetes. Leptin deficiency reduces metablic rate. Leptin deficient mice are less active and with lower body temperature than normal animals. Human Leptin shares approximately 84% sequence identity with the mouse protein. Human Leptin consists of 167 amino acid residue including a 21 amino acid residue signal sequence and 146 amino acid residue mature protein sequence.
BP000221-CYT-507: Recombinant Rabbit Leptin (LEP) Protein
Source: E. Coli-derived.
A single, non-glycosylated, polypeptide chain containing 146 amino acids and having a molecular mass of 16 kDa.
N-terminal sequence analysis: Ala-Val-Pro-Ile-Arg.
Biological active as evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor.
Purity: > 95.0% by reducing SDS-PAGE and SEC-HPLC.
Formulation: The protein was lyophilized from a concentrated (1 mg/ml) solution with 0.0045 mM NaHCO3.
Reconstitution: It is recommended to reconstitute the lyophilized Leptin in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-?thaw cycles.
12 months from date of receipt, -20 to -?70? as supplied.
Other LEP Proteins:
Recombinant Salamander LEP Protein
Recombinant Rat Leptin Protein
Recombinant Porcine LEP Protein
Recombinant Ovine Leptin Protein
Recombinant Mouse LEP Protein
Recombinant Human Leptin Protein, His Tag
Recombinant Human Leptin Protein
Recombinant Human Leptin Protein
Recombinant Human LEP Protein
Recombinant Horse LEP Protein
Recombinant Dog LEP Protein
Recombinant Chicken LEP Protein
Recombinant Bovine Leptin Protein
Recombinant Chicken LEP Protein
Recombinant Rat Pegylated LEP Protein
Copyright © 2009-2022 sydlabs.com. All rights reserved.
Use of this website means that you have read, understood, and accepted the Syd Labs Privacy Policy and Terms & Conditions.