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    74 products and services containing "erbb"
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  • C039P: Abciximab Biosimilar (Research Grade), Anti-human Glycoprotein IIb/IIIa Receptor Monoclonal Antibody

    Recombinant Humanized IgG1 Monoclonal Antibody.
    Specificity/Sensitivity: The monoclonal antibody abciximab biosimilar specifically binds to the human Glycoprotein IIb/IIIa Receptor protein.
    Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by abciximab.

  • APIM050072: ACALABRUTINIB (ACP196)

    CAS No.: 1420477-60-6.
    Purity: >99.5% chem and optical purity by achiral and chiral HPLCs.
    QC: HPLC-MS, Chiral HPLC, 1HNMR and Quantitative Elemental Analysis.
    Solubility: Refer to Certificate.

  • APIM050072: ACALABRUTINIB (ACP196)

    CAS No.: 1420477-60-6.
    Purity: >99.5% chem and optical purity by achiral and chiral HPLCs.
    QC: HPLC-MS, Chiral HPLC, 1HNMR and Quantitative Elemental Analysis.
    Solubility: Refer to Certificate.

  • C003P: Adalimumab Biosimilar, TNF alpha Monoclonal Antibody

    Recombinant Humanized IgG1 Monoclonal Antibody.
    Specificity/Sensitivity: The monoclonal antibody adalimumab biosimilar specifically binds to the human TNF alpha.
    Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by adalimumab.

  • C040P: Alemtuzumab Biosimilar, CD52 Monoclonal Antibody

    Recombinant Humanized IgG1 Monoclonal Antibody.
    Specificity/Sensitivity: The monoclonal antibody alemtuzumab biosimilar specifically binds to the human CD52, a protein present on the surface of mature lymphocytes.
    Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by alemtuzumab.

  • PA007565.m2a: In Vivo Grade Recombinant Anti-human EGFR Monoclonal Antibody (Clone: 528), Mouse IgG2a Kappa

    Recombinant mouse IgG2a Monoclonal Antibody.
    Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: 528) specifically binds to human EGFR.
    Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human EGFR protein.

     

  • PA007575.m1:In Vivo Grade Recombinant Anti-human EGFR Monoclonal Antibody (Clone: 225), Mouse IgG1 Kappa

    Recombinant Mouse IgG1 Monoclonal Antibody.
    Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: 225) specifically binds to human EGFR.
    Applications:ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human EGFR protein.

  • C001P: Bevacizumab Biosimilar, Human VEGF Monoclonal Antibody

    Recombinant Humanized IgG1 Monoclonal Antibody generated from the same parent mouse antibody as ranibizumab.
    Specificity/Sensitivity: The monoclonal antibody bevacizumab biosimilar specifically binds to the human VEGF-A.
    Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by bevacizumab.

  • BP005627: Biotinylated Human EGFR/HER1 Protein with the C-His-Avi Tag

    Source: The recombinant Biotinylated Human EGFR/HER1 Protein, (amino acids Leu25-Ser645) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
    Activity: Immobilized recombinant Biotinylated Human EGFR protein with the C-His-Avi tag at 1 ug/ml (100 ul/well) on the streptavidin precoated plate(5 ug/ml). Dose response curve for the recombinant Human EGF protein with the C-hFc tag with the EC50 of 5.5 ng/ml determined by ELISA (QC Test). The affinity constant of 0.62 nM as determined in SPR assay (Biacore T200).
    Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
    Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

  • BP005314: Biotinylated Human EGFRVIII Protein with the C-His-Avi Tag

    Source: The recombinant Biotinylated Human EGFRVIII Protein, (amino acids Leu25-Ser378) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
    Activity: Immobilized recombinant Biotinylated Human EGFRVIII protein with the C-His-Avi tag at 0.5 ug/ml (100 ul/Well) on streptavidin (5 ug/ml) precoated plate. Dose response curve for the recombinant Anti-EGFR VIII Anitibody protein with the C-hFc tag with the EC50 of 4.8 ng/ml determined by ELISA (QC Test).
    Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
    Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

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