C109P: Tusamitamab Biosimilar, CEACAM5 Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The research grade tusamitamab biosimilar specifically binds to the CEACAM5 protein.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by tusamitamab.

BP004367: Mouse CEACAM-1/CD66a Protein with the C-His Tag

Source: The recombinant Mouse CEACAM-1/CD66a Protein, (amino acids Glu35-Gly428) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005059: Human CEACAM-8/CD66b Protein with the C-His Tag

Source: The recombinant Human CEACAM-8/CD66b Protein, (amino acids Gln35-Ser319) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: The affinity constant of 4.59 uM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003154: Human CEACAM-7 Protein with the C-His Tag

Source: The recombinant Human CEACAM-7 Protein, (amino acids Thr36-Ser242) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human CEACAM-7 protein with the C-His tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human CEACAM-3 protein with the C-hFc tag with the EC50 of 31.1 ng/ml determined by ELISA (QC Test). The affinity constant of 0.37 uM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003093: Human CEACAM-7 Protein with the C-hFc Tag

Source: The recombinant Human CEACAM-7 Protein, (amino acids Thr36-Ser242) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human CEACAM-3 protein with the C-hFc tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human CEACAM-7 protein with the C-hFc tag with the EC50 of 26.5 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005640: Human CEACAM-6/CD66c Protein with the C-His-Avi Tag

Source: The recombinant Human CEACAM-6/CD66c Protein, (amino acids Lys35-Gly320) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: The affinity constant of 4.59 uM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003113: Human CEACAM-5/CD66e (323-500) Protein with the C-His Tag

Source: The recombinant Human CEACAM-5/CD66e (323-500) Protein, (amino acids Pro323-Leu500) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003264: Human CEACAM-5/CD66e Protein with the C-His Tag

Source: The recombinant Human CEACAM-5/CD66e Protein, (amino acids Lys35-Ala685) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human CEACAM-5 protein with the C-His tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-CEACAM5 Antibody protein with the C-hFc tag with the EC50 of 8.3 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003114: Human CEACAM-5/CD66e (145-322) Protein with the C-His Tag

Source: The recombinant Human CEACAM-5/CD66e (145-322) Protein, (amino acids Pro145-Pro322) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003118: Human CEACAM-5/CD66e (501-685) Protein with the C-His Tag

Source: The recombinant Human CEACAM-5/CD66e (501-685) Protein, (amino acids Pro501-Ala685) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human CEACAM-5 protein with the C-His tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-CEACAM5 Antibody protein with the C-hFc tag with the EC50 of 28.8 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003167: Human CEACAM-3 Protein with the C-His Tag

Source: The recombinant Human CEACAM-3 Protein, (amino acids Lys35-Gly155) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human CEACAM-3 protein with the C-His tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human CEACAM-7 protein with the C-hFc tag with the EC50 of 26.5 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003171: Human CEACAM-3 Protein with the C-hFc Tag

Source: The recombinant Human CEACAM-3 Protein, (amino acids Lys35-Gly155) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human CEACAM-7 protein with the C-hFc tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human CEACAM-3 protein with the C-hFc tag with the EC50 of 31.1 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.