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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal IL-1β Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Interleukin-1b is produced by activated macrophages, IL-1B stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL1B proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. IL-1b is an inflammatory cytokine which modulates angiogenesis by interacting directly with vascular endothelial cells & increasing the production of proangiogenic factors through paracrine control. IL-1 beta stimulates endothelial cell migration and proliferation, adhesion-molecule expression, inflammatory mediator production, and leukocyte recruitment. IL1B is essential for tumor growth, metastasis, and angiogenesis in quite a few animal models.
BP000132-CYT-718: Recombinant Rhesus Macaque IL-1β Protein
Source: E. coli-derived.
A non-glycosylated, Polypeptide chain containing 153 amino acids and having a molecular mass of 17.3 kDa.
The ED50 as determined by the dose-dependant stimulation of D10.G4.1 mouse helper T cells is typically 3-10 pg/mL.
Purity: > 98% by SDS-PAGE and RP-HPLC.
Formulation: The protein was lyophilized with 1x PBS pH-7.4
Reconstitution: It is recommended to reconstitute the lyophilized IL1B in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other IL-1 beta Proteins:
Recombinant Mouse IL-1β
Recombinant Human IL-1β Protein, His Tag
Recombinant Porcine IL-1β
Recombinant Human IL-1β
Recombinant Human IL-1β, HEK
Recombinant Rat IL-1β
Recombinant Mouse IL-1β Protein
Recombinant Mouse IL-1β Protein, His Tag
IL-1 beta Antibodies:
IL-1 beta Polyclonal Antibody
IL1B Polyclonal Antibody
IL1B Polyclonal Antibody
IL-1 beta ELISA Kits:
Human IL-1β ELISA Kit
Human IL-1RA ELISA Kit
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