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Epo-R Antibody

EPO-R, EPOR, Erythropoietin receptor precursor

Catalog No. Product Name Size List Price (US$) Quantity
PA001596-PA2032 Epo-R Polyclonal Antibody 100 ug 350.00
Description

Background

EPOR (Erythropoietin Receptor), is a protein that in humans is encoded by the EPOR gene. Jones et al. (1990) isolated the human homolog of the murine erythropoietin receptor (EPOR) from an erythroleukemia cell line and from fetal liver. Budarf et al. (1990) mapped the EPOR gene to human 19pter-q12 by somatic cell hybrid analysis. Akashi et al. (2000) reported the prospective identification, purification, and characterization, using cell surface markers and flow cytometry, of a complementary clonogenic common myeloid progenitor that gives rise to all myeloid lineages. The distinction between the common lymphoid progenitor and common myeloid progenitor is that the common lymphoid progenitor expresses IL7 receptor and does not express MPL, whereas the common myeloid progenitor does not express the IL7 receptor and expresses MPL. Becker et al. (2010) showed by mathematical modeling of quantitative data and experimental validation that rapid ligand depletion and replenishment of the cell surface receptor are characteristic features of the EPO receptor.

PA001596-PA2032: Epo-R Polyclonal Antibody

Rabbit Polyclonal Antibody.
Applications: WB 0.1-0.5 ug/ml.
Reactivity: Human, Mouse.
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human EPOR, identical to the related mouse sequence, and different from the related rat sequence by three amino acids.
Purification: Immunogen affinity purified.
Form of Antibody: Lyophilized. Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Reconstitution: Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at 20 °C and 3 months at 4 °C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Other Epo-R Antibody:
Epo-R (Ab-368) Polyclonal Antibody

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