APIM050347: CB-839 (TELAGLENASTAT)
CAS No.: 1439399-58-2.
Purity: 99.9% by HPLC.
QC: HPLC, 1H-NMR and Quantitative Elemental Analysis Report.
Solubility: Refer to Certificate of Analysis.APIM050131: CO-1686 (ROCILETINIB)
CAS No.: 1374640-70-6.
Purity: >99.5% (HPLC at 214 and 254 nm).
QC: HPLC-MS, 1HNMR and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.C057P: Obinutuzumab Biosimilar, CD20 Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade obinutuzumab biosimilar specifically binds to the human type II CD20 antibodies.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by obinutuzumab.EK0300: Rapid Mouse Monoclonal Antibody Isotyping Test Kit A
The rapid mouse antibody isotyping test kit A is a five-minute lateral flow assay with ELISA sensitivity for monoclonal antibody class and subclass determination. It can be used to determine the isotype of IgG1, IgG2a, IgG2b, IgG3, IgA, and IgM, as well as kappa and lambda in one test kit. There are two cassettes in the test kit, one for IgG1, IgG2a, IgG2b, and IgG3, and the other for kappa, Lamda, IgA, and IgM.
Sample requirements: hybridoma culture supernatant and purified monoclonal antibody. Although ascites fluid is not recommended since there is usually multiple immunoglobulins, the kit can be used to determine the relative distribution of the main isotypes in the ascites fluid.
Note: BALB/c and DBA mice produce IgG2a, not IgG2c. And C57BL/6, C57BL/10, SJL and NOD mice produce IgG2c, not IgG2a.
Sensitivity: Minimal detection limit is 100 ng/ml.
Specificity: There is no cross-reactivity among each isotype.C072P: Envafolimab Biosimilar, PD-L1 Monoclonal Antibody
Recombinant humanized nanobody (VHH-hIgG1 Fc fusion protein) .
Specificity/Sensitivity: The in vivo grade envafolimab specifically binds to the human PDL1 protein.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by envafolimab.PA007179: In Vivo Grade Recombinant Anti-HIV V1V2 Loop Glycan Human IgG1 Kappa Monoclonal Antibody
The in vivo grade recombinant anti-HIV V1V2 loop glycan human IgG1 monoclonal antibody (clone of PGDM1400) was produced in mammalian cells.
Applications: ELISA, Western blot, immunohistochemistry (IHC), Flow Cytometry (FC), and various in vitro and in vivo functional assays.APIM050078: AP26113 (BRIGATINIB)
CAS No.: 1197953-54-0.
Purity: >99% by HPLC.
QC: HPLC-MS, NMR and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.APIM050026: BLU-667 (Pralsetinib)
CAS No.: 2097132-94-8.
Purity: >99% chemical and optical purity by achiral and chiral HPLCs.
QC: Achiral and Chiral HPLCs, MS, 1H-NMR, and Quantitative Elemental Analysis Report.
Solubility: refer to Certificate of Analysis.APIM050072: ACALABRUTINIB (ACP196)
CAS No.: 1420477-60-6.
Purity: >99.5% chem and optical purity by achiral and chiral HPLCs.
QC: HPLC-MS, Chiral HPLC, 1HNMR and Quantitative Elemental Analysis.
Solubility: Refer to Certificate.APIM050023: BGB-283 (Lifirafenib)
CAS No.: 1446090-77-2.
Purity: >99.5% chem and optical purity by achiral and chiral HPLCs.
QC: HPLC-MS, 1H-NMR, Chiral HPLC, and Elemental Analysis Report.
Solubility: Refer to Certificate.