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CEA Protein

Carcinoembryonic Antigen, oncofetal antigen

Catalog No. Product Name Size List Price (US$) Quantity
BP001552-PRO-287 Recombinant Human Carcinoembryonic Antigen Protein 10 ug 160.00
BP001552-PRO-287 Recombinant Human Carcinoembryonic Antigen Protein 1 mg 2800.00
Description

Introduction
Carcinoembryonic antigen (CEA) is a glycoprotein present in fetal digestive-tract tissues; it? involved in cell adhesion. The production of CEA stops before birth. CEA is called tumor marker since its elevated levels are found in the serum from individuals with colorectal, gastric, pancreatic, lung and breast carcinomas and in heavy smokers.
There are also benign conditions that elevate CEA levels such as smoking, infection, inflammatory bowel disease, pancreatitis, cirrhosis of the liver, and some benign tumors (in the equivalent organs which have cancers with elevated CEA). Typically, higher levels of CEA are found in men, smokers, and older individuals.
The presence of CEA assists in screening, in evaluating recurrent or disseminated disease, and in determining the success of surgical removal of malignant tumors.
CEA levels can be used as indicators of treatment success. The normal values range from 0.0 to 2.5 ng/ml of serum (from blood), in non-smokers, a greater amount than that may be suggestive of cancer. Levels above 20 ng/ml before treatment are associated with cancer which has already metastasized. Benign conditions do not usually cause a CEA increase over 10 ng/ml.
The high levels of CEA should return to normal after successful therapy, however if during follow up there an elevation in CEA levels it indicates a recurrence of tumor.
Carcinoembryonic antigen family belongs to the immunoglobulin superfamily; it consists of 29 genes, 18 of which are normally expressed.

BP001552-PRO-287: Recombinant Human Carcinoembryonic Antigen (CEA) Protein

Source: E. coli-derived.
Predicted molecular mass: 120,000 Dalton.
Purity: > 90.0% as determined by SDS-PAGE.
Formulation: The sterile protein solution contains 10 mM NaH2PO4, pH 7 and 150 mM NaCl.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

CEA Antibodies:
CEA Polyclonal Antibody
CEA Monoclonal Antibody
CEA Monoclonal Antibody
CEA Monoclonal Antibody
CEA Monoclonal Antibody

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