My Cart [ 0 ]
Home > Antibodies > Anti-Mouse Antibodies (In Vivo) > Anti-Mouse TCR V gamma 2 Monoclonal Antibodies

Anti-Mouse TCR V gamma 2 Monoclonal Antibodies

V gamma 2 T-cell receptor, T cell receptor gamma 2, TCR V gamma 4

Catalog No. Product Name Size List Price (US$) Quantity
PA007571.m2a In Vivo Grade Recombinant Anti-mouse TCR V gamma 2 Monoclonal Antibody (Clone: UC3-10A6), Mouse IgG2a Kappa 1 mg 150.00
PA007571.m2a In Vivo Grade Recombinant Anti-mouse TCR V gamma 2 Monoclonal Antibody (Clone: UC3-10A6), Mouse IgG2a Kappa 5 mg 350.00
PA007571.m2a In Vivo Grade Recombinant Anti-mouse TCR V gamma 2 Monoclonal Antibody (Clone: UC3-10A6), Mouse IgG2a Kappa 25 mg 900.00
PA007571.hs In Vivo Grade Recombinant Anti-mouse TCR V gamma 2 Monoclonal Antibody (Clone: UC3-10A6), Armenian hamster IgG Kappa 1 mg 150.00
PA007571.hs In Vivo Grade Recombinant Anti-mouse TCR V gamma 2 Monoclonal Antibody (Clone: UC3-10A6), Armenian hamster IgG Kappa 5 mg 350.00
PA007571.hs In Vivo Grade Recombinant Anti-mouse TCR V gamma 2 Monoclonal Antibody (Clone: UC3-10A6), Armenian hamster IgG Kappa 25 mg 900.00
Description

PA007571.m2a: In Vivo Grade Recombinant Anti-mouse TCR V gamma 2 Monoclonal Antibody (Clone: UC3-10A6), Mouse IgG2a Kappa

Recombinant mouse IgG2a Monoclonal Antibody.
Clone: UC3-10A6.
Isotype: Mouse IgG2a kappa.
Source: The anti-mouse TCR V gamma 2 monoclonal antibody (clone: UC3-10A6) was produced in mammalian cells.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: UC3-10A6) specifically binds to mouse TCR V gamma 2.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse TCR V gamma 2 protein.
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin: < 1 EU per 1 mg of the protein by the LAL method.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.

PA007571.hs: In Vivo Grade Recombinant Anti-mouse TCR V gamma 2 Monoclonal Antibody (Clone: UC3-10A6), Armenian hamster IgG Kappa

Recombinant hamster IgG Monoclonal Antibody.
Clone: UC3-10A6.
Isotype: Armenian hamster IgG Kappa.
Source: The anti-mouse TCR V gamma 2 monoclonal antibody (clone: UC3-10A6) was produced in mammalian cells.
Specificity/Sensitivity: The in vivo grade recombinant hamster  monoclonal antibody (clone: UC3-10A6) specifically binds to mouse TCR V gamma 2.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse TCR V gamma 2 protein.
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin: < 1 EU per 1 mg of the protein by the LAL method.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.

Shipping: The in vivo grade recombinant anti-mouse TCR V gamma 2 monoclonal antibody of clone UC3-10A6 is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month from date of receipt, 2 to 8°C as supplied.

References of Anti-Mouse TCR V gamma 2 Monoclonal Antibody (Clone: UC3-10A6)

Rezende, R. M., et al. Nat Commun. 2018 Aug 8;9(1):3151. doi: 10.1038/s41467-018-05487-9. PMID: 30089795
Importantly, CXCR5 expression was only upregulated on Vγ1 γδ T cells after CFA immunization. ...To investigate the involvement of different subtypes of γδ T cells on their ability to control the humoral immune response, 200 μg of anti-Vγ2 mAb (“anti-Vγ4”; UC3-10A6; BioXCell) or isotype control (BioXCell) were injected i.p. three days before either CFA or Alum immunization and three days before OVA booster dose. ...Consistent with the increased levels of OVA-specific immunoglobulins following Vγ4 γδ T cell depletion, we found that Tfh cell frequency was higher in Vγ4 γδ T cell-depleted mice than in isotype control (IC)-treated mice immunized with CFA/OVA, but not after Alum/OVA immunization. ...Importantly, TCRδ-/- mice transferred with CXCR5-/- γδ T cells had decreased Tfh cell frequencies and did not develop GC following CFA immunization as compared to mice transferred with WT γδ T cells. ...Thus, CXCR5 expression on γδ T cells is induced by γδTCR activation.
(Tags: function of anti-mouse TCR V gamma 2 UC3-10A6 antibody; bioactivity of anti-mouse TCR V gamma 2 UC3-10A6)
For more technical references or data sheets regarding the Recombinant Anti-Mouse TCR V gamma 2 Monoclonal Antibody (Clone: UC3-10A6) formats, please contact our scientific support team at message@sydlabs.com.
Related Links

See our Privacy Policy