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Recombinant rat IgG2a isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Recombinant Rat IgG2a Monoclonal Antibody.
Clone: KM703.
Isotype: Rat IgG2a Kappa.
Source: The anti-mouse CD44 monoclonal antibody (clone: KM703) was produced in mammalian cells.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: KM703) specifically binds to mouse CD44.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD44 protein.
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin: < 1 EU per 1 mg of the protein by the LAL method.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.
Shipping: The in vivo grade recombinant anti-mouse CD44 monoclonal antibody of clone KM703 is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month from date of receipt, 2 to 8°C as supplied.
Predominance of CD4 Th1 and CD8 Tc1 cells revealed by characterization of the cellular immune response generated by immunization with a DNA vaccine containing a Trypanosoma cruzi gene.
Rodrigues, M. M., et al. Infect Immun. 1999 Aug;67(8):3855-63. doi: 10.1128/IAI.67.8.3855-3863.1999. PMID: 10417149
The rat IgG MAbs used for staining were anti-CD8 2.43, anti-CD4 GK1.5, anti-CD44 KM 703, and anti-VLA-4/LPAM-1 R1-2. ...In addition, they expressed high levels of CD44 and detectable levels of VLA-4 (CD49d), two surface molecules that have been implicated in the antiparasitic activity of CD8 T cells. ...Expression of CD8, CD44, and VLA-4 surface molecules in clones A4 and A10. ...We thank Zuleica Caulada, ICB-USP, for helping with the FACS analysis, Moriya Tsuji for helping with the CD4 clones, and Mariano Levin and Sergio Schenkman for comments on the manuscript. ...The presence of IFN-γ-producing splenic cells of DNA-immunized mice was estimated 6 days after in vitro expansion upon stimulation with A20J-TS cells.
Tags: anti-mouse CD44 KM703 in cancer research; anti-mouse CD44 KM703 antibody in cancer research
For more references about Anti-mouse CD44 Monoclonal Antibody please contact our scientific support team with message@sydlabs.com.
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