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Home > Antibodies > Anti-Mouse Antibodies (In Vivo) > Anti-Mouse CD24 Monoclonal Antibodies

Anti-Mouse CD24 Monoclonal Antibodies

CD 24, CD24 molecule, CD24A, FLJ22950, FLJ43543, MGC75043

Catalog No. Product Name Size List Price (US$) Quantity
PA007623.r2b In Vivo Grade Recombinant Anti-mouse CD24 Monoclonal Antibody (Clone: M1/69.16.11.HL), Rat IgG2b Kappa 1 mg 150.00
PA007623.r2b In Vivo Grade Recombinant Anti-mouse CD24 Monoclonal Antibody (Clone: M1/69.16.11.HL), Rat IgG2b Kappa 5 mg 350.00
PA007623.r2b In Vivo Grade Recombinant Anti-mouse CD24 Monoclonal Antibody (Clone: M1/69.16.11.HL), Rat IgG2b Kappa 25 mg 900.00
Description

PA007623.r2b: In Vivo Grade Recombinant Anti-mouse CD24 Monoclonal Antibody (Clone: M1/69.16.11.HL), Rat IgG2b Kappa

Recombinant Rat IgG2b Monoclonal Antibody.
Clone: M1/69.16.11.HL.
Isotype: Rat IgG2b Kappa.
Source: The anti-mouse CD24 monoclonal antibody (clone: M1/69.16.11.HL) was produced in mammalian cells.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: M1/69.16.11.HL) specifically binds to mouse CD24.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD24 protein.
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin: < 1 EU per 1 mg of the protein by the LAL method.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.

Shipping: The in vivo grade recombinant anti-mouse CD24 monoclonal antibody of clone M1/69.16.11.HL is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month from date of receipt, 2 to 8°C as supplied.

References of Anti-Mouse CD24 Monoclonal Antibody (Clone: M1/69.16.11.HL)

Chen Y, et al. Front Immunol. 2022 Apr 15;13:855181. doi: 10.3389/fimmu.2022.855181. PMID: 35559385
CD24-deficient Treg cells exhibited more potent suppressive capacity in inhibiting the development of experimental autoimmune encephalomyelitis (EAE) in mice. A representative proliferation assay using Tconv cells from CD24-/-C57BL6 mice as responder, irradiated splenocytes from CD24-/-Rag1-/- mice as APC in the presence and absence of different concentrations of anti-CD24 mAb (M1/69.16.11.HL). In vivo transfer of CD24-deficient Tregs into EAE recipient mice delayed disease onset. FoxP3+ Treg cells from CD24 knockout mice produced higher levels of IL-10 in vivo. Suppressive function of Tregs was enhanced in CD24-deficient mice during EAE induction.
(Tags: anti-mouse CD24 M1/69.16.11.HL in vivo; anti-mouse CD24 M1/69.16.11.HL antibody in vivo)
Yang X, et al. J Immunol. 2015 Jun 1;194(11):5337-45. doi: 10.4049/jimmunol.1403079. PMID: 25934567
Colitis-induced mice were adoptively transferred with Tregs treated ex vivo with anti-mouse CD24 (M1/69.16.11.HL) before in vivo assessment. Anti-mouse CD24 blockade impaired Treg suppressive function in vivo. In vivo colitis scores were higher in recipients of anti-mouse CD24-treated Tregs. CD24+ Tregs were essential for mucosal tolerance in the model. IL-10 production by Tregs was reduced post-anti-mouse CD24 exposure.
(Tags: function of anti-mouse CD24 M1/69.16.11.HL mAb; bioactivity of anti-mouse CD24 M1/69.16.11.HL mAb)
For more technical references or data sheets regarding the Recombinant Anti-Mouse CD24 Monoclonal Antibody (Clone: M1/69.16.11.HL) formats, please contact our scientific support team at message@sydlabs.com.
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