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Conditions of optimal UBE2C Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
UbcH10 is an essential mediator of mitotic destruction events and cell cycle progression. It catalyzes the destruction of cyclins A and B in conjunction with the anaphase-promoting complex, and therefore, plays an important role in the control of the cell exit from mitosis. This activity is essential at then end of mitosis for the inactivation of their partner kinase Cdc2 and exit from mitosis into G1 of the next cell cycle. In addition, UbcH10 bears homology to yeast PAS2, a gene that is essential for biogenesis of peroxisomes. UbcH10 is useful for in vitro ubiquitinylation reactions.
BP000976-ENZ-346: Recombinant Human Ubiquitin Conjugating enzyme E2C (UBE2C) Enzyme
Source: E. coli-derived.
Predicted molecular mass: 21.1 kDa.
Purity: > 90% by SDS-PAGE.
Formulation: UBE2C protein 1 ug/ml is supplied in 20 mM Tris-HCL, pH-8, 0.15 M NaCl, 1 mM DTT and 10% Glycerol.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other UBE2C Enzymes:
Recombinant Human UBE2C Enzyme
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