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UBE2C Enzyme

Ubiquitin-conjugating enzyme E2 C, EC 6.3.2.19, Ubiquitin-protein ligase C, Ubiquitin carrier protein C, Ubc10, UBCH10, dJ447F3

Catalog No. Product Name Size List Price (US$) Quantity
BP000976-CF41 Recombinant Human UBE2C Enzyme 10 ug 98.00
BP000976-CF41 Recombinant Human UBE2C Enzyme 50 ug 342.00
BP000976-CF41 Recombinant Human UBE2C Enzyme 1 mg 2640.00
Description

Introduction
UbcH10 is an essential mediator of mitotic destruction events and cell cycle progression. It catalyzes the destruction of cyclins A and B in conjunction with the anaphase-promoting complex, and therefore, plays an important role in the control of the cell exit from mitosis. This activity is essential at then end of mitosis for the inactivation of their partner kinase Cdc2 and exit from mitosis into G1 of the next cell cycle. In addition, UbcH10 bears homology to yeast PAS2, a gene that is essential for biogenesis of peroxisomes. UbcH10 is useful for in vitro ubiquitinylation reactions.

BP000976-CF41: Recombinant Human Ubiquitin Conjugating enzyme E2C (UBE2C) Enzyme

Source: E. coli-derived.
Recombinant Human Ubiquitin Conjugating enzyme E2C (UBE2C) Enzyme is expressed with sequence (Met1-Pro179) of Human UBE2C fused with a 6His tag at the N-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).
Formulation: 0.2 um filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, pH 7.5.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

Other UBE2C Enzymes:
Recombinant Human UBE2C Enzyme

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