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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal TNFβ Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Tumor Necrosis Factor β (TNF-β) is a secreted protein belonging to the tumor necrosis factor family. TNF-β binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM in homotrimeric form, binds to TNFRSF3/LTBR in heterotrimeric form with LTB. TNF-β forms heterotrimers with lymphotoxin-beta, which anchors TNF-β to the cell surface. TNF-β mediates the inflammatory, immunostimulatory, and antiviral response, involves in the formation of second lymphoid organs during development, has a role in apoptosis. TNF-β is produced by lymphocytes and cytotoxic for a variety of tumor cells in vitro and in vivo.
BP000124-CYT-224: Recombinant Human Tumor Necrosis Factor β (TNFβ) Protein
Source: E. coli-derived.
A single, non-glycosylated, polypeptide chain containing 172 amino acids and having a molecular mass of 18645 Dalton.
The ED50 as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D is < 0.05 ug/ml, corresponding to a Specific Activity of 20 MIU/mg.
Purity: > 98% by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized protein with no additives.
Reconstitution: It is recommended to reconstitute the lyophilized Tumor Necrosis Factor-beta in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other TNF beta Proteins:
Recombinant Human TNFβ Protein
Recombinant Human TNFβ Protein
Recombinant Human TNFβ Protein, His Tag
TNF beta Antibodies:
TNFβ Polyclonal Antibody
TNFβ Polyclonal Antibody
TNF beta ELISA Kit:
Human TNFβ ELISA Kit
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