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Conditions of optimal SNAP25 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Introduction
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, SNAP25 product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. The synaptosomal-associated protein (SNAP-25) is an essential component of the core complex that mediates presynaptic vesicle trafficking. Thus, SNAP-25 is directly involved in the release of neurotransmitters.
BP002041-PRO-573: Recombinant Human Synaptosomal-associated 25 kDa protein (SNAP25)
Source: E. coli-derived.
Recombinant Human Synaptosomal-associated 25 kDa protein (SNAP25) fused to N-terminal His-Tag is a single, non-glycosylated polypeptide chain containing 226 amino acids and having a molecular mass of 25.4 kDa.
Purity: > 95.0% as determined by (a) Analysis by RP-HPLC; (b) Analysis by SDS-PAGE.
Formulation: The protein solution contains 20 mM Tris-HCl pH 7.5, 1 mM EDTA, 50 mM NaCl and 2 mM DTT.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other SNAP25 Protein:
Recombinant C.elegans SNAP25 Protein
SNAP25 Antibodies:
SNAP25 Polyclonal Antibody
SNAP25 Polyclonal Antibody
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