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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal SMAD3 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
SMAD3 is part of the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD3 has a role as a transcriptional modulator activated by TGF-Beta and is involved in the regulation of carcinogenesis. SMAD3 mutations are related with the pathogenesis of human osteoarthritis. SMAD3 expression take part in tumor suppression in the premature stages of gastric carcinogenesis. SMAD3 is involved in nuclear translocation of beta-catenin.
BP002072-PRO-751: Recombinant Human Mothers Against Decapentaplegic Homolog 3 (SMAD3) protein
Source: E. Coli-derived.
Recombinant Human Mothers Against Decapentaplegic Homolog 3 (SMAD3) protein is a single, non-glycosylated polypeptide chain containing 445 amino acids (1-425) and having a molecular mass of 50.2 kDa. Recombinant Human Mothers Against Decapentaplegic Homolog 3 (SMAD3) protein is fused to a 20 amino acid His-Tag at N-Terminus and purified by standard chromatography techniques.
Purity: > 90.0% as determined by SDS-PAGE.
Formulation: The SMAD3 protein solution contains 20 mM Tris-HCl pH 8, 0.1 M NaCl, 0.1 mM DTT and 20% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
SMAD3 Antibodies:
Smad3 (Ab-425) Polyclonal Antibody
Smad3 (Ab-213) Polyclonal Antibody
Smad3 (Ab-204) Polyclonal Antibody
Smad3 (Ab-179) Polyclonal Antibody
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