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Conditions of optimal PTX2 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Introduction
Serum Amyoid P Component (SAP), also known as APCS and Pentraxin 2 (PTX2), is a monomeric 25 kDa secreted serum glycoprotein that belongs to the pentraxins family. The members of pentaxin superfamily be characterised by calcium dependent ligand binding and distinctive flattened ?-jellyroll structure similar to that of the legume lectins. APCS is non-fibrillar component, can interact with DNA and histones. It regulates the solubility of amyloid fibrils and protects them from degradation by proteolytic enzymes and phagocytic cells. APCS scavenge nuclear material released from damaged circulating cells. It has been proposed that APCS may function as an opsonin for a variety of ligands including autoantigens, apoptotic cells, chromatin and micro-organisms.
BP002120-PRO-453: Recombinant Human Serum Amyloid P-Component (SAP) Protein
Source: E. Coli-derived.
Recombinant Human Amyloid P Component (APCS) Protein is a non-glycosylated, polypeptide chain having a molecular weight of 23.5 kDa.
APCS contains T7 tag at N-terminus and is purified by proprietary chromatographic techniques.
Applications: ELISA; MS; Western Blotting.
Purity: > 95.0% by SDS-PAGE.
Formulation: APCS containing 10 mM Tris, pH 8.0, 0.01% Triton X-100 and 0.002% NaN3 and 10 mM DTT.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other SAP Proteins:
Recombinant Human SAP Protein
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