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Conditions of optimal PTX2 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Introduction
Serum Amyoid P Component (SAP), also known as APCS and Pentraxin 2 (PTX2), is a monomeric 25 kDa secreted serum glycoprotein that belongs to the pentraxins family. The members of pentaxin superfamily be characterised by calcium dependent ligand binding and distinctive flattened ?-jellyroll structure similar to that of the legume lectins. APCS is non-fibrillar component, can interact with DNA and histones. It regulates the solubility of amyloid fibrils and protects them from degradation by proteolytic enzymes and phagocytic cells. APCS scavenge nuclear material released from damaged circulating cells. It has been proposed that APCS may function as an opsonin for a variety of ligands including autoantigens, apoptotic cells, chromatin and micro-organisms.
BP001137-C510: Recombinant Human Serum Amyloid P-Component (SAP) Protein
Source: HEK 293-derived.
Recombinant Human Serum Amyloid P-Component/SAP is a secreted protein with sequence (His20-Val223) of human APCS fused with a polyhistidine tag at the C-terminus.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 EU/ug).
Formulation: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other SAP Proteins:
Recombinant Human SAP Protein
Recombinant Human SAP18 Protein
SAP Antibodies:
SAP 155 Polyclonal Antibody
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