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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal PMM2 Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Phosphomannomutase 2 (PMM2) is a member of the eukaryotic PMM family. Phosphomannomutase 2 is involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. PMM2 catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate. PMM2 mutations are linked to congenital disorders of glycosylation (CDG)-Ia, an autosomal recessive disorder characterized by central nervous system dysfunction and multiorgan failure.
BP000668-ENZ-002: Recombinant Human Phosphomannomutase 2 (PMM2) Enzyme
Source: E. coli-derived.
A single, non-glycosylated, polypeptide chain containing 266 amino acids (1-246 a.a.) and having a molecular mass of 30.2 kDa.
Purity: > 95% by SDS-PAGE.
Formulation: The PMM2 solution (1 ug/ml) contains 20 mM Tris-HCl buffer(pH 8.0), 10% glycerol, 1 mM DTT and 0.1 MNaCl.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other PMM2 Enzymes:
Recombinant Human PMM2 Enzyme
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