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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal PKAkt1/PKBa Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Akt1, also known as "Akt" or protein kinaseB (PKB) is an important molecule in mammaliancellular signaling.
In humans, there are three genes in the "Akt family": Akt1, Akt2, and Akt3. These enzymesare members of the serine/threonine-specific protein kinasefamily (EC2.7.11.1).
Akt1 is involved in cellular survival pathways, by inhibiting apoptoticprocesses. Akt1 is also able to induce protein synthesispathways, and is therefore a key signaling protein in the cellular pathways that lead to skeletal muscle hypertrophy, and general tissue growth. Since it can block apoptosis, and thereby promote cell survival, Akt1 has been implicated as a major factor in many types of cancer. Akt (now also called Akt1) was originally identified as the oncogenein the transforming retrovirus, AKT8.
BP000810-PKA-206: Recombinant Human Protein Kinase Akt1/PKBa, Active enzyme
Source: Sf9 insect cells-derived.
Predicted molecular mass: 59.1 kDa.
Purity > 90%, by SDS-PAGE.
Formulation: PKAkt1 1.9 mg/ml, in 50 mM NaCl, 1 mM DTT, 25 mM beta glycerophosphate, 50% glycerol, pH 8.5.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other PKAkt1/PKBa Enzymes:
Recombinant Human Protein Kinase Akt1/PKBα, Inactive enzyme
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