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Conditions of optimal p53 (Phosphorylated) antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Background
The p53 tumor antigen is found in increased amounts in a wide variety of transformed cells. The protein is also detectable in many actively proliferating, nontransformed cells, but it is undetectable or present at low levels in resting cells. This protein induces cell cycle arrest or apoptosis in response to sublethal or severe DNA damage, respectively, by differential transcription of target genes and through transcription-independent apoptotic functions. The p53 protein contains 393 amino acids. Human p53 tumour antigen is Locatedto band 17p13. p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis.
PA000071-P7010: p53 (phospho-37) Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Recognize only phosphor p53 in human, not mouse.
Applications: ELISA, 1: 2500 WB, 1:2500.
Immunogen: phosphor p53 peptide (ser-37) KLH conjugates.
Purification: Peptide-affinity chromatography.
Form of Antibody: 250 ug/mL in PBS, pH7 with 50% Glycerol + 0.01% NaZ3.
Storage/Stability: Stable for 1 year at -20°C and 3 months at -20°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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