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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal p38 MAPK antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background
MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38?, p38?and p38?, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38?, p38?and p38? are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation. The p38 proteins are subject to phosphoryation on Thr and Tyr residues, an event which is thought to activate the phosphorylated protein.
PA000418-P9890: p38 Hog (p38?, MAPK) Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Recognize p38 ? MAPK of human, mouse, rat, not cross-react with p38 ? and ?.
Applications: ELISA (0.5 ug/ml), WB (1 ug/ml), IP (5 ug/sample).
Immunogen: human p38 ? c-terminal peptide (SFVPPPLDQEEMES)-KLH conjugates.
Purification: The antibody is affinity purified with SFVPPPLDQEEMES on agarose.
Form of Antibody: 250 ? g/mL in 0.1 M TBS, 0.01% NaN3.
Storage/Stability: Stable for 1 year at -20°C and 3 months at -20°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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